SCHEMBL6859042

SCHEMBL6859042

c1ccc2c(c1)ccc1[nH]nnc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.50
NPC1 O15118 5/20 0.50
ALDH1A1 P00352 6/20 0.42
KDM4E B2RXH2 4/20 0.42
MAPT P10636 3/20 0.42
HPGD P15428 2/20 0.42
TP53 P04637 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
HSD17B10 Q99714 3/20 0.42
CYP2A6 P11509 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
TSHR P16473 1/20 0.42
MEN1 O00255 2/20 0.41
POLB P06746 2/20 0.41
KMT2A Q03164 2/20 0.41
HTT P42858 1/20 0.41
GAA P10253 1/20 0.40
HPRT1 P00492 1/20 0.39
SIRT2 Q8IXJ6 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31502563 1.00 RAB9A (0.50) RAB9ANPC1ALDH1A1KDM4EMAPT
SCHEMBL1547836 0.91 HPRT1 (0.50) RAB9ANPC1ALDH1A1KDM4EMAPT
SCHEMBL31285952 0.91 HPRT1 (0.50) RAB9ANPC1ALDH1A1KDM4EMAPT
SCHEMBL3179279 0.83 ALDH1A1 (0.38) RAB9ANPC1ALDH1A1KDM4EMAPT
Phosphonic Acid SCHEMBL31285967 0.82 HPRT1 (0.41) RAB9ANPC1ALDH1A1KDM4EMAPT
SCHEMBL31285939 0.81 HPRT1 (0.40) RAB9ANPC1ALDH1A1KDM4EMAPT
SCHEMBL17145024 0.78 BCHE (0.41) RAB9ANPC1ALDH1A1KDM4EMAPT
SCHEMBL9511534 0.76 ITK (0.42) ALDH1A1KDM4EMAPTHPGDHSD17B10
SCHEMBL31412089 0.75 KDM4E (0.42) RAB9ANPC1ALDH1A1KDM4EMAPT
SCHEMBL9374740 0.74 LMNA (0.61) ALDH1A1KDM4EMAPTTP53SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030019055-A1 Reactive dye mixture DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2003-01-30 US claimed
EP-1196502-A2 REACTIVE DYE MIXTURES DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2002-04-17 EP claimed
WO-2001000736-A2 REACTIVE DYE MIXTURES DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2001-01-04 WO claimed
WO-2018147638-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME 주식회사 두산 2018-08-16 WO disclosed
US-6800099-B2 DIAZO, MONOAZO, AZOPYRIDONE, AZONAPHTHYL, DIAZOAMINONAPHTHYL, FORMAZAN, AND TRIPHENODIOXAZINE DYES DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2004-10-05 US disclosed
US-20030019055-A1 Reactive dye mixture DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2003-01-30 US disclosed
EP-1196502-A2 REACTIVE DYE MIXTURES DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2002-04-17 EP disclosed
WO-2001000736-A2 REACTIVE DYE MIXTURES DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2001-01-04 WO disclosed
US-6143434-A HIGH LUMINANCE AND A HIGH LUMINESCENT EFFICIENCY AT A LOW DRIVING VOLTAGE AND HAS EXCELLENT STABILITY IN REPETITIONS OF USE FUJI PHOTO FILM CO., LTD. (JP) 2000-11-07 US disclosed
EP-0647878-B1 Silver halide photographic material FUJI PHOTO FILM CO LTD (JP) 2000-01-12 EP disclosed
EP-0474047-B1 Silver halide emulsion FUJI PHOTO FILM CO LTD (JP) 1996-06-12 EP disclosed
US-5093222-A Contrast, negatives FUJI PHOTO FILM CO., LTD. (JP) 1992-03-03 US disclosed
EP-0439356-A1 Spectrally sensitized silver halide photographic material KONICA CORPORATION (JP) 1991-07-31 EP disclosed
US-4925777-A Direct positives FUJI PHOTO FILM CO., LTD. (JP) 1990-05-15 US disclosed
US-4740455-A Heat developable light-sensitive material containing polymethine FUJI PHOTO FILM CO., LTD. (JP) 1988-04-26 US disclosed
US-4725532-A CONTAINING HYDRAZIDE DERIVATIVE, CATIONIC DYE AND ASCORBIC ACID FUJI PHOTO FILM CO., LTD. (JP) 1988-02-16 US disclosed
EP-0044009-A2 Process for the preparation of 2-(2,2,2,-Trichloro-1-hydroxy-ethyl) phenols BAYER AG (DE) 1982-01-20 EP disclosed
US-4284704-A Photographic elements with incorporated hydrogen source photoreductant and tetrazolium salt EASTMAN KODAK COMPANY (US) 1981-08-18 US disclosed
US-4220694-A TRIAZOLE-COATED NEGATIVE ELECTRODE COLLECTOR HITACHI MAXELL, LTD. (JP) 1980-09-02 US disclosed
EP-0005823-A1 Leak-proof alkaline cell and its production Hitachi Maxell Ltd. (JP) 1979-12-12 EP disclosed