Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 10/20 | 0.75 |
| ▸ | PGR | P06401 | 6/20 | 0.75 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.75 |
| ▸ | LMNA | P02545 | 3/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.75 |
| ▸ | USP2 | O75604 | 1/20 | 0.75 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.75 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.75 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.59 |
| ▸ | AR | P10275 | 2/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.58 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.58 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.58 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | TNF | P01375 | 1/20 | 0.54 |
| ▸ | IL6 | P05231 | 1/20 | 0.54 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.54 |
| ▸ | GLUL | P15104 | 1/20 | 0.54 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6859081 | 1.00 | NR3C1 (0.75) | NR3C1PGRHIF1ALMNACYP3A4 | |
| SCHEMBL6852141 | 0.96 | NR3C1 (0.71) | NR3C1PGRHIF1ALMNACYP3A4 | |
| SCHEMBL6859066 | 0.94 | NR3C1 (0.69) | NR3C1PGRHIF1ALMNACYP3A4 | |
| SCHEMBL6859064 | 0.94 | NR3C1 (0.69) | NR3C1PGRHIF1ALMNACYP3A4 | |
| SCHEMBL6859129 | 0.94 | NR3C1 (0.68) | NR3C1PGRHIF1ALMNACYP3A4 | |
| SCHEMBL6859128 | 0.94 | NR3C1 (0.68) | NR3C1PGRHIF1ALMNACYP3A4 | |
| SCHEMBL6856718 | 0.93 | NR3C1 (0.69) | NR3C1PGRHIF1ALMNACYP3A4 | |
| SCHEMBL6856722 | 0.93 | NR3C1 (0.69) | NR3C1PGRHIF1ALMNACYP3A4 | |
| SCHEMBL7598868 | 0.93 | NR3C1 (0.82) | NR3C1PGRHIF1ALMNACYP3A4 | |
| SCHEMBL6858944 | 0.92 | NR3C1 (0.68) | NR3C1PGRHIF1ALMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6835724-B2 | Topical antiinflammatory agents for treating inflammatory dermatoses | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-12-28 | — | — | US | disclosed |
| US-20020103392-A1 | CORTICOID-17,21-DICARBOXYLIC ESTERS AND CORTICOSTEROID 17-CARBOXYLIC ESTER 21-CARBONIC ESTERS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICALS CONTAINING THESE COMPOUNDS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-08-01 | — | — | US | disclosed |
| EP-0646593-A1 | Corticoid-17,21-dicarboxylic acid ester and corticosteroid-17-carboxylic acid ester-21-carbonic, process for their production and medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-04-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020103392-A1 | CORTICOID-17,21-DICARBOXYLIC ESTERS AND CORTICOSTEROID 17-CARBOXYLIC ESTER 21-CARBONIC ESTERS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICALS CONTAINING THESE COMPOUNDS | NR3C1, HSD3B1, HSD17B7 | NR3C1 1/4885PGR 707/4885HIF1A 2813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.