Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 2/20 | 0.31 |
| ▸ | GABRD | O14764 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.31 |
| ▸ | GABRE | P78334 | 2/20 | 0.31 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.31 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.31 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.31 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL393554 | 0.84 | — | — | |
| SCHEMBL29448013 | 0.75 | — | — | |
| SCHEMBL20550625 | 0.75 | — | — | |
| Oxalic Acid SCHEMBL28080051 | 0.73 | GABRP (0.48) | ALOX15SLC1A3SLC1A2SLC1A1GABRP | |
| Oxalic Acid SCHEMBL7607255 | 0.69 | SLC1A3 (0.44) | ALOX15SLC1A3SLC1A2SLC1A1GABRP | |
| Oxalic Acid SCHEMBL28309748 | 0.69 | TSHR (0.67) | ALOX15FFAR3TSHRALDH1A1 | |
| SCHEMBL4721437 | 0.69 | FFAR3 (0.33) | FFAR3TSHRNPY5R | |
| SCHEMBL15514628 | 0.68 | — | — | |
| Oxalic Acid SCHEMBL9516907 | 0.67 | ALOX15 (0.39) | ALOX15FFAR3TSHRALDH1A1 | |
| SCHEMBL20798325 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1241225-A2 | Resins acting as wet strength agents and creping aids and processes for preparing and using the same | HERCULES INCORPORATED (US) | 2002-09-18 | — | — | EP | claimed |
| EP-1241225-B1 | Resins acting as wet strength agents and creping aids and processes for preparing and using the same | HERCULES INC (US) | 2004-11-17 | — | — | EP | disclosed |
| US-20030114631-A1 | Resins acting as wet strength agents and creping aids and processes for preparing and using the same | HERCULES CORPORATION | 2003-06-19 | — | — | US | disclosed |
| EP-1241225-A2 | Resins acting as wet strength agents and creping aids and processes for preparing and using the same | HERCULES INCORPORATED (US) | 2002-09-18 | — | — | EP | disclosed |