Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6836066 | 0.88 | POLB (0.32) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL6847745 | 0.87 | LMNA (0.31) | LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL5854455 | 0.81 | LMNA (0.33) | LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL6840561 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL5853577 | 0.80 | KCNK3 (0.32) | LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL6702088 | 0.78 | KMT2A (0.34) | LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL7074019 | 0.78 | NPSR1 (0.37) | KMT2A | |
| Hydrochloric Acid SCHEMBL6843568 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL5856658 | 0.77 | SIGMAR1 (0.34) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL6843687 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004106394-A1 | COPOLYMERS OF ETHYLENE AND/OR α-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-12-09 | — | — | WO | disclosed |