Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TET3 | O43151 | 1/20 | 0.45 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.45 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.45 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.45 |
| ▸ | CXXC4 | Q9H2H0 | 1/20 | 0.45 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17220377 | 0.86 | SCD5 (0.57) | SCD5KMT2ATET3FBXL19CXXC5 | |
| SCHEMBL25168805 | 0.83 | SCD5 (0.47) | DRD2SCD5KMT2AHSD11B1KDM4E | |
| SCHEMBL558749 | 0.82 | MEN1 (0.54) | DRD2KMT2AOPRD1OPRK1SMN1; SMN2 | |
| SCHEMBL3646332 | 0.78 | SCD5 (0.48) | DRD2SCD5OPRM1OPRD1OPRK1 | |
| SCHEMBL28819411 | 0.78 | DRD2 (0.46) | DRD2DRD4DRD3OPRM1OPRD1 | |
| SCHEMBL16245128 | 0.78 | DRD2 (0.48) | DRD2KMT2ADRD4DRD3OPRM1 | |
| SCHEMBL5371462 | 0.78 | OPRM1 (0.47) | DRD2DRD4DRD3OPRM1OPRD1 | |
| SCHEMBL2229509 | 0.78 | MEN1 (0.62) | DRD2KMT2ADRD4DRD3KDM4E | |
| SCHEMBL23706066 | 0.77 | SCD5 (0.52) | SCD5KMT2ATET3FBXL19CXXC5 | |
| SCHEMBL3931269 | 0.76 | KMT2A (0.71) | KMT2ATET3FBXL19CXXC5KDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448566-A2 | CHEMOKINE RECEPTOR ANTAGONISTS AND METHODS OF USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2004-08-25 | — | — | EP | disclosed |
| WO-2003045942-A2 | CHEMOKINE RECEPTOR ANTAGONISTS AND METHODS OF USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2003-06-05 | — | — | WO | disclosed |