Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6866314 | 0.83 | MAOA (0.37) | KMT2AKDM4ELMNAPOLBCYP3A4 | |
| SCHEMBL6865846 | 0.74 | MAOA (0.37) | KMT2AKDM4ELMNAPOLBCYP3A4 | |
| SCHEMBL6407853 | 0.71 | MAOA (0.40) | KMT2AKDM4ELMNAPOLBCYP3A4 | |
| SCHEMBL20256433 | 0.66 | MAOA (0.53) | MAPTMAOAALDH1A1RAB9A | |
| SCHEMBL6412752 | 0.66 | HPGD (0.48) | KMT2AKDM4ELMNAPOLBCYP3A4 | |
| SCHEMBL6865318 | 0.65 | MAOA (0.40) | KMT2AKDM4ELMNAPOLBCYP3A4 | |
| SCHEMBL6409833 | 0.65 | MAOA (0.40) | KMT2AKDM4ELMNAPOLBCYP3A4 | |
| SCHEMBL6408125 | 0.65 | KMT2A (0.50) | KMT2AKDM4ELMNAPOLBCYP3A4 | |
| SCHEMBL6407332 | 0.65 | CYP1A1 (0.34) | — | |
| SCHEMBL20256677 | 0.65 | S100A4 (0.49) | KMT2ATDP1MAOAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6809096-B1 | SUCH AS 11-METHOXY-7H-PYRIDO(4,3,2-DE)(1,7)PHENANTHROLINE-7-ONE; ANTITUMOR AGENTS | LABORATOIRE L. LAFON (FR) | 2004-10-26 | — | — | US | disclosed |