Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.34 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6866314 | 0.87 | MAOA (0.37) | MAOAMAPTKDM4ELMNAMAPK1 | |
| SCHEMBL6410245 | 0.77 | ALDH1A1 (0.35) | MAPTKDM4ELMNAMAPK1TDP1 | |
| SCHEMBL6409833 | 0.75 | MAOA (0.40) | MAOAMAPTKDM4ELMNAMAPK1 | |
| SCHEMBL6859938 | 0.75 | MAOA (0.40) | MAOAMAPTKDM4ELMNAMAPK1 | |
| SCHEMBL6407178 | 0.74 | MAPT (0.50) | MAOAMAPTKDM4ELMNAMAPK1 | |
| SCHEMBL6859768 | 0.74 | KMT2A (0.34) | MAOAMAPTKDM4ELMNAMAPK1 | |
| SCHEMBL6414875 | 0.72 | ALDH1A1 (0.34) | MAPTKDM4ELMNAMAPK1TDP1 | |
| SCHEMBL7182934 | 0.68 | TERT (0.57) | MAOAKDM4EHTTPOLBHPGD | |
| SCHEMBL6414255 | 0.68 | HTT (0.34) | MAOAMAPTKDM4ELMNAMAPK1 | |
| SCHEMBL6407305 | 0.66 | HPGD (0.48) | MAOAMAPTKDM4ELMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6809096-B1 | SUCH AS 11-METHOXY-7H-PYRIDO(4,3,2-DE)(1,7)PHENANTHROLINE-7-ONE; ANTITUMOR AGENTS | LABORATOIRE L. LAFON (FR) | 2004-10-26 | — | — | US | disclosed |