SCHEMBL6859985

SCHEMBL6859985

C=CC(=O)C(N)CCC(=O)O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM8 O00222 1/20 0.60
GRM6 O15303 1/20 0.60
GRIN2D O15399 1/20 0.60
GRIN3B O60391 1/20 0.60
GSR P00390 1/20 0.60
CYP1A2 P05177 1/20 0.60
GRIK1 P39086 1/20 0.60
GRM5 P41594 1/20 0.60
GRIA1 P42261 1/20 0.60
GRIA2 P42262 1/20 0.60
GRIA3 P42263 1/20 0.60
SLC1A3 P43003 1/20 0.60
SLC1A2 P43004 1/20 0.60
SLC1A1 P43005 1/20 0.60
GRIA4 P48058 1/20 0.60
GRIN1 Q05586 1/20 0.60
GRIN2A Q12879 1/20 0.60
GRIK2 Q13002 1/20 0.60
GRIK3 Q13003 1/20 0.60
GRIN2B Q13224 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13074161 1.00 GRM8 (0.60) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL17335980 0.87 BLM (0.50) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL29665718 0.85 ENPEP (0.50) GRM8GRM6GRIN2DGRIN3BGSR
Succinic Acid SCHEMBL28838042 0.83 CYP2D6 (0.45) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL10663621 0.82 TSHR (0.39) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL311669 0.82 CYP1A2 (0.60) GRM8GRM6GRIN2DGRIN3BGSR
D-Glutamate SCHEMBL28761652 0.81 GRM8 (0.72) GRM8GRM6GRIN2DGRIN3BGSR
Glutamic Acid SCHEMBL3734632 0.81 GRM8 (0.72) GRM8GRM6GRIN2DGRIN3BGSR
D-Glutamate SCHEMBL3734630 0.81 GRM8 (0.72) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL9015306 0.79 TSHR (0.40) GRM8GRM6GRIN2DGRIN3BGSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6794467-B2 CROSSLINKING; FREE RADICAL CATALYST; SWELLING WITH ALCOHOL; DISPOSABLE PRODUCTS; DIAPERS, SANITARY NAPKINS COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2004-09-21 US claimed
CN-108467460-A A kind of high intensity can heal polyvinyl alcohol hydrogel and preparation method thereof 长春工业大学 2018-08-31 CN disclosed
US-6794467-B2 CROSSLINKING; FREE RADICAL CATALYST; SWELLING WITH ALCOHOL; DISPOSABLE PRODUCTS; DIAPERS, SANITARY NAPKINS COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2004-09-21 US disclosed