SCHEMBL311669

SCHEMBL311669

N[C@@H](CCC(=O)O)C(=O)C=O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.60
GRM8 O00222 1/20 0.60
GRM6 O15303 1/20 0.60
GRIN2D O15399 1/20 0.60
GRIN3B O60391 1/20 0.60
GSR P00390 1/20 0.60
GRIK1 P39086 1/20 0.60
GRM5 P41594 1/20 0.60
GRIA1 P42261 1/20 0.60
GRIA2 P42262 1/20 0.60
GRIA3 P42263 1/20 0.60
SLC1A3 P43003 1/20 0.60
SLC1A2 P43004 1/20 0.60
SLC1A1 P43005 1/20 0.60
GRIA4 P48058 1/20 0.60
GRIN1 Q05586 1/20 0.60
GRIN2A Q12879 1/20 0.60
GRIK2 Q13002 1/20 0.60
GRIK3 Q13003 1/20 0.60
GRIN2B Q13224 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29788447 0.87 ENPEP (0.48) CYP1A2GRM8GRM6GRIN2DGRIN3B
SCHEMBL13074161 0.82 GRM8 (0.60) CYP1A2GRM8GRM6GRIN2DGRIN3B
SCHEMBL6859985 0.82 GRM8 (0.60) CYP1A2GRM8GRM6GRIN2DGRIN3B
Glutamic Acid SCHEMBL1469880 0.80 GRM8 (0.78) CYP1A2GRM8GRM6GRIN2DGRIN3B
D-Glutamate SCHEMBL6519183 0.80 GRM8 (0.78) CYP1A2GRM8GRM6GRIN2DGRIN3B
Glutamic Acid SCHEMBL5053703 0.77 GRM8 (0.82) CYP1A2GRM8GRM6GRIN2DGRIN3B
D-Glutamate SCHEMBL910530 0.77 GRM8 (0.82) CYP1A2GRM8GRM6GRIN2DGRIN3B
D-Glutamate SCHEMBL27856487 0.77 GRM8 (0.82) CYP1A2GRM8GRM6GRIN2DGRIN3B
Glutamic Acid SCHEMBL910249 0.77 GRM8 (0.82) CYP1A2GRM8GRM6GRIN2DGRIN3B
SCHEMBL10632175 0.77 GRM8 (0.54) CYP1A2GRM8GRM6GRIN2DGRIN3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10786562-B2 Interaction of moraxella catarrhalis with epithelial cells, extracellular matrix proteins and the complement system ARNE FORSGREN AB (SE) 2020-09-29 US disclosed
US-20190117757-A1 INTERACTION OF MORAXELLA CATARRHALIS WITH EPITHELIAL CELLS, EXTRACELLULAR MATRIX PROTEINS AND THE COMPLEMENT SYSTEM ARNE FORSGREN AB (SE) 2019-04-25 US disclosed
US-10183071-B2 Interaction of moraxella catarrhalis with epithellal cells, extracellular matrix proteins and the complement system ARNE FORSGREN AB (SE) 2019-01-22 US disclosed
EP-3305807-A1 INTERACTION OF MORAXELLA CATARRHALIS WITH EPITHELIAL CELLS, EXTRACELLULAR MATRIX PROTEINS AND THE COMPLEMENT SYSTEM Arne Forsgren AB (SE) 2018-04-11 EP disclosed
EP-2548885-B1 INTERACTION OF MORAXELLA CATARRHALIS WITH EPITHELIAL CELLS, EXTRACELLULAR MATRIX PROTEINS AND THE COMPLEMENT SYSTEM ARNE FORSGREN AB (SE) 2017-10-18 EP disclosed
US-20170281746-A1 INTERACTION OF MORAXELLA CATARRHALIS WITH EPITHELLAL CELLS, EXTRACELLULAR MATRIX PROTEINS AND THE COMPLEMENT SYSTEM ARNE FORSGREN AB (SE) 2017-10-05 US disclosed
EP-2548884-B1 Interaction of moraxella catarrhalis with epithelial cells, extracellular matrix proteins and the complement system ARNE FORSGREN AB (SE) 2017-08-02 EP disclosed
US-9657067-B2 Interaction of moraxella catarrhalis with epithelial cells, extracellular matrix proteins and the complement system ARNE FORSGREN AB (SE) 2017-05-23 US disclosed
US-20160318979-A1 INTERACTION OF MORAXELLA CATARRHALIS WITH EPITHELIAL CELLS, EXTRACELLULAR MATRIX PROTEINS AND THE COMPLEMENT SYSTEM ARNE FORSGREN AB (SE) 2016-11-03 US disclosed
US-9255127-B2 Interaction of Moraxella catarrhalis with epithelial cells, extracellular matrix proteins and the complement system ARNE FORSGREN AB (SE) 2016-02-09 US disclosed
EP-2548884-A2 Interaction of moraxella catarrhalis with epithelial cells, extracellular matrix proteins and the complement system Arne Forsgren AB (SE) 2013-01-23 EP disclosed
EP-2548885-A2 Interaction of moraxella catarrhalis with epithelial cells, extracellular matrix proteins and the complement system Arne Forsgren AB (SE) 2013-01-23 EP disclosed
US-8323667-B2 Interaction of Moraxella catarrhalis with epithelial cells, extracellular matrix proteins and the complement system ARNE FORSGREN AB (SE) 2012-12-04 US disclosed
CN-101243104-B Interaction of moraxella catarrhalis with epithelial cells, extracellular matrix proteins and the complement system ARNE FORSGREN AB 2012-07-18 CN disclosed
US-20120148614-A1 Interaction of Moraxella Catarrhalis with Epithelial Cells, Extracellular Matrix Proteins and the Complement System ARNE FORSGREN AB 2012-06-14 US disclosed
US-8092811-B2 Interaction of Moraxella catarrhalis with epithelial cells, extracellular matrix proteins and the complement system ARNE FORSGREN AB (SE) 2012-01-10 US disclosed
US-20100062027-A1 INTERACTION OF MORAXELLA CATARRHALIS WITH EPITHELIAL CELLS, EXTRACELLULAR MATRIX PROTEINS AND THE COMPLEMENT SYSTEM ARNE FORSGREN AB (SE) 2010-03-11 US disclosed
CN-101243104-A Interaction of moraxella catarrhalis with epithelial cells, extracellular matrix proteins and the complement system ARNE FORSGREN AB (SE) 2008-08-13 CN disclosed
EP-1913019-A2 INTERACTION OF MORAXELLA CATARRHALIS WITH EPITHELIAL CELLS, EXTRACELLULAR MATRIX PROTEINS AND THE COMPLEMENT SYSTEM Arne Forsgren AB (SE) 2008-04-23 EP disclosed
WO-2007018463-A2 INTERACTION OF MORAXELLA CATARRHALIS WITH EPITHELIAL CELLS, EXTRACELLULAR MATRIX PROTEINS AND THE COMPLEMENT SYSTEM ARNE FORSGREN AB (SE) 2007-02-15 WO disclosed