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Sugi Predict / Compounds / Glutamine

Glutamine

Glutamine

SCHEMBL6860246

CC(C)[C@H](N)C(=O)O.CC(C)[C@H](N)C(=O)O.CC(C)[C@H](N)C(=O)O.CC(C)[C@H](N)C(=O)O.C[C@H](N)C(=O)O.C[C@H](N)C(=O)O.NC(=O)CC[C@H](N)C(=O)O.NC(=O)CC[C@H](N)C(=O)O.NCC(=O)O.NCC(=O)O.N[C@@H](CS)C(=O)O.N[C@@H](CS)C(=O)O.N[C@@H](CS)C(=O)[O-].N[C@@H](CS)C(=O)[O-].O=C(O)[C@@H]1CCCN1.O=C(O)[C@@H]1CCCN1.[Cu+2]

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

SLC5A2

The experimentally established mechanism targets of Glutamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ ALOX15 P16050 1/20 0.33
▸ BLM P54132 1/20 0.33
▸ PMP22 Q01453 1/20 0.33
▸ KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutamine SCHEMBL6369942 0.96 ALOX15 (0.35) ALOX15BLMPMP22KMT2A
Glutamine SCHEMBL3047068 0.95 ALOX15 (0.36) ALOX15BLMPMP22KMT2A
Glutamine SCHEMBL5664624 0.95 ALOX15 (0.36) ALOX15BLMPMP22KMT2A
Glutamine SCHEMBL6371387 0.95 ALOX15 (0.36) ALOX15BLMPMP22KMT2A
Glutamine SCHEMBL6860254 0.94 ALOX15 (0.36) ALOX15BLMPMP22KMT2A
Glutamine SCHEMBL5665046 0.91 ALOX15 (0.40) ALOX15BLMPMP22KMT2A
Glutamine SCHEMBL6377469 0.91 ALOX15 (0.40) ALOX15BLMPMP22KMT2A
Valine SCHEMBL6368983 0.91 SLC7A5 (0.31) —
Glutamine SCHEMBL6369944 0.90 ALOX15 (0.39) ALOX15BLMPMP22KMT2A
Glutamine SCHEMBL5663861 0.90 ALOX15 (0.40) ALOX15BLMPMP22KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6794362-B1 TOPICAL COSMETIC APPLIED AS EMULSION, LOTION, SPRAY, POWDER, OINTMENT, CREAM, INCREASES SKIN'S TURGOR CONNECTIVE TISSUE IMAGINEERING LLC 2004-09-21 — — US disclosed
US-6506731-B1 Peptide or peptide-like compound(s) of the present invention appear to aid the elasticity and/or turgor of the skin CONNECTIVE TISSUE IMAGINEERING LLC 2003-01-14 — — US disclosed