Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glutamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glutamine SCHEMBL5664624 | 1.00 | ALOX15 (0.36) | ALOX15BLMPMP22KMT2APTGS1 | |
| Glutamine SCHEMBL6860254 | 0.99 | ALOX15 (0.36) | ALOX15BLMPMP22KMT2APTGS1 | |
| Glutamine SCHEMBL5665046 | 0.96 | ALOX15 (0.40) | ALOX15BLMPMP22KMT2APTGS1 | |
| Glutamine SCHEMBL6377469 | 0.96 | ALOX15 (0.40) | ALOX15BLMPMP22KMT2APTGS1 | |
| Glutamine SCHEMBL6369944 | 0.95 | ALOX15 (0.39) | ALOX15BLMPMP22KMT2APTGS1 | |
| Glutamine SCHEMBL5663861 | 0.95 | ALOX15 (0.40) | ALOX15BLMPMP22KMT2A | |
| Glutamine SCHEMBL6860246 | 0.95 | ALOX15 (0.33) | ALOX15BLMPMP22KMT2A | |
| Glutamine SCHEMBL5665397 | 0.94 | ALOX15 (0.41) | ALOX15BLMPMP22KMT2APTGS1 | |
| Glutamine SCHEMBL6517171 | 0.94 | ALOX15 (0.41) | ALOX15BLMPMP22KMT2APTGS1 | |
| Glutamine SCHEMBL6371388 | 0.93 | ALOX15 (0.40) | ALOX15BLMPMP22KMT2APTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6962904-B1 | Elastin peptide analogs and uses thereof | CONNECTIVE TISSUE IMAGINEERING (US) | 2005-11-08 | — | — | US | claimed |
| US-7666842-B2 | Elastin peptide analogs and uses thereof | Connective Tissue Imagineering, LLC (US) | 2010-02-23 | — | — | US | disclosed |
| US-6794362-B1 | TOPICAL COSMETIC APPLIED AS EMULSION, LOTION, SPRAY, POWDER, OINTMENT, CREAM, INCREASES SKIN'S TURGOR | CONNECTIVE TISSUE IMAGINEERING LLC | 2004-09-21 | — | — | US | disclosed |
| US-6506731-B1 | Peptide or peptide-like compound(s) of the present invention appear to aid the elasticity and/or turgor of the skin | CONNECTIVE TISSUE IMAGINEERING LLC | 2003-01-14 | — | — | US | disclosed |