Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | KCNJ6 | P48051 | 2/20 | 0.33 |
| ▸ | KCNJ5 | P48544 | 2/20 | 0.33 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.30 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6444240 | 0.86 | NPC1 (0.33) | KCNJ6KCNJ5KCNJ3NPC1RAB9A | |
| SCHEMBL2638398 | 0.86 | KDM4E (0.34) | KCNJ6KCNJ5KCNJ3NPC1RAB9A | |
| SCHEMBL2637632 | 0.85 | TLR8 (0.34) | NPC1RAB9ACYP3A4CYP2D6TP53 | |
| SCHEMBL16182319 | 0.84 | FFAR1 (0.39) | — | |
| SCHEMBL769298 | 0.84 | NPC1 (0.36) | NPC1RAB9ACYP3A4CYP2D6KDM4E | |
| SCHEMBL29376453 | 0.84 | NPC1 (0.36) | NPC1RAB9ACYP3A4CYP2D6KDM4E | |
| SCHEMBL13715027 | 0.83 | ALDH1A1 (0.34) | KCNJ6KCNJ5KCNJ3MC4RTSHR | |
| SCHEMBL2638154 | 0.83 | TRPV1 (0.38) | — | |
| SCHEMBL5873319 | 0.83 | TRPV1 (0.38) | — | |
| SCHEMBL769171 | 0.83 | NPC1 (0.36) | NPC1RAB9ACYP3A4CYP2D6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6800676-B2 | ULTRAVIOLET RADIATION ABSORBERS; HEAT AND OXIDATION RESISTANCE | CIBA SPECIALTY CHEMICALS CORPORATION | 2004-10-05 | — | — | US | claimed |