Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KDM4A | O75164 | 1/20 | 0.49 |
| ▸ | TDP2 | O95551 | 1/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2458682 | 1.00 | PDE7A (0.56) | PDE7ASMN1; SMN2MAPTALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL10637432 | 0.98 | PDE7A (0.55) | PDE7ASMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL224666 | 0.82 | PDE7A (0.60) | PDE7ASMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL31272173 | 0.82 | PDE7A (0.78) | PDE7ASMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL875772 | 0.82 | PDE7A (0.78) | PDE7ASMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL2588027 | 0.82 | GPR35 (0.58) | PDE7ASMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL2588026 | 0.82 | GPR35 (0.58) | PDE7ASMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL3263406 | 0.80 | TDP1 (0.64) | PDE7ASMN1; SMN2MAPTALDH1A1KMT2A | |
| SCHEMBL1896221 | 0.80 | PDE7A (0.58) | PDE7ASMN1; SMN2MAPTALDH1A1MEN1 | |
| SCHEMBL3384869 | 0.80 | PDE7A (0.58) | PDE7ASMN1; SMN2MAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1409482-A2 | DYE-SULFENATES FOR DUAL PHOTOTHERAPY | MALLINCKRODT INC. (US) | 2004-04-21 | — | — | EP | disclosed |
| WO-2003004466-A2 | DYE-SULFENATES FOR DUAL PHOTOTHERAPY | MALLINCKRODT INC. (US) | 2003-01-16 | — | — | WO | disclosed |