SCHEMBL68607

SCHEMBL68607

C#CCOc1ccc(CCC(=O)NC(C#N)c2ccc(Cl)cc2)cc1OC

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.47
HDAC1 Q13547 4/20 0.46
HDAC2 Q92769 4/20 0.46
MEN1 O00255 3/20 0.44
GAA P10253 1/20 0.41
ALDH1A1 P00352 1/20 0.41
UTS2R Q9UKP6 1/20 0.41
LMNA P02545 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CNR1 P21554 1/20 0.40
PPARG P37231 1/20 0.40
RAB9A P51151 1/20 0.40
NCOA3 Q9Y6Q9 1/20 0.40
P2RX7 Q99572 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29419114 1.00 KMT2A (0.47) KMT2AHDAC1HDAC2MEN1GAA
SCHEMBL5687932 0.96 KMT2A (0.47) KMT2AHDAC1HDAC2MEN1GAA
SCHEMBL5688303 0.94 LMNA (0.41) KMT2AHDAC1HDAC2MEN1UTS2R
SCHEMBL5685372 0.94 KMT2A (0.50) KMT2AHDAC1HDAC2MEN1ALDH1A1
SCHEMBL1547475 0.92 LMNA (0.48) KMT2AHDAC1HDAC2MEN1GAA
SCHEMBL5686001 0.92 KMT2A (0.48) KMT2AHDAC1HDAC2MEN1ALDH1A1
SCHEMBL5685043 0.92 KMT2A (0.49) KMT2AHDAC1HDAC2MEN1GAA
SCHEMBL5685476 0.92 KMT2A (0.48) KMT2AHDAC1HDAC2MEN1ALDH1A1
SCHEMBL5685018 0.92 KMT2A (0.48) KMT2AHDAC1HDAC2MEN1ALDH1A1
SCHEMBL5685030 0.91 KMT2A (0.46) KMT2AHDAC1HDAC2MEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1400 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108658816-B N-aryl amidine substituted trifluoroethyl sulfide derivatives useful as acaricides and insecticides 拜尔农作物科学股份公司 2023-05-02 CN claimed
CN-108184905-B Compositions comprising biological control agents and fungicides 拜尔农作物科学股份公司 2021-12-28 CN claimed
CN-107996613-B Compositions comprising biological control agents and pesticides 拜尔农作物科学股份公司 2021-10-22 CN claimed
CN-107926985-B Compositions comprising biological control agents and fungicides 拜尔农作物科学股份公司 2021-02-02 CN claimed
EP-3488700-B1 COMPOSITION COMPRISING A BIOLOGICAL CONTROL AGENT AND A FUNGICIDE BAYER CROPSCIENCE AG (DE) 2020-12-16 EP claimed
EP-2854545-B1 COMPOSITIONS COMPRISING A BIOLOGICAL CONTROL AGENT AND AN INSECTICIDE BAYER CROPSCIENCE AG (DE) 2020-10-21 EP claimed
CN-106962403-B Compositions comprising biological control agents and pesticides 拜耳作物科学股份公司 2020-05-05 CN claimed
EP-3010893-B1 ARYLSULFIDE AND ARYLSULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES BAYER CROPSCIENCE AG (DE) 2019-10-02 EP claimed
EP-2854532-B1 COMPOSITIONS COMPRISING A BIOLOGICAL CONTROL AGENT AND AN INSECTICIDE BAYER CROPSCIENCE AG (DE) 2019-08-07 EP claimed
US-20190159451-A1 ACTIVE COMPOUND COMBINATIONS AND METHODS TO PROTECT THE PROPAGATION MATERIAL OF PLANTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-05-30 US claimed
WO-2009090181-A2 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE BAYER CROPSCIENCE SA (FR) 2009-07-23 WO claimed
EP-2014167-A1 Active compound combinations Bayer CropScience AG (DE) 2009-01-14 EP claimed
WO-2008152092-A2 PESTICIDAL COMPOSITION COMPRISING A STRIGOLACTONE DERIVATIVE AND AN FUNGICIDE COMPOUND BAYER CROPSCIENCE SA (FR) 2008-12-18 WO claimed
WO-2008142029-A1 METHOD FOR IMPROVING THE BUD QUALITY OF A PLANT BAYER CROPSCIENCE SA (FR) 2008-11-27 WO claimed
WO-2008128654-A2 USE OF FUNGICIDES FOR TREATING FISH MYCOSES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2008-10-30 WO claimed
EP-1982717-A1 Use of fungicides for treating fish mycoses Bayer CropScience AG (DE) 2008-10-22 EP claimed
EP-1898709-A1 FUNGICIDE COMPOSITION COMPRISING A PHOSPHOROUS ACID DERIVATIVE, A MANDELAMIDE TYPE COMPOUND AND A FURTHER FUNGICIDE COMPOUND Bayer CropScience S.A. (FR) 2008-03-19 EP claimed
WO-2006136551-A1 FUNGICIDE COMPOSITION COMPRISING A PHOSPHOROUS ACID DERIVATIVE, A MANDELAMIDE TYPE COMPOUND AND A FURTHER FUNGICIDE COMPOUND BAYER CROPSCIENCE SA (FR) 2006-12-28 WO claimed
WO-2005122766-A1 FUNGICIDAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-12-29 WO claimed
EP-1609360-A1 Fungicidal Composition Sumitomo Chemical Company, Limited (JP) 2005-12-28 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190159451-A1 ACTIVE COMPOUND COMBINATIONS AND METHODS TO PROTECT THE PROPAGATION MATERIAL OF PLANTS BROX, CAT, MPG KMT2A 3113/4885HDAC1 3438/4885HDAC2 3731/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.