SCHEMBL5685476

SCHEMBL5685476

C#CCOc1ccc(CCC(=O)NC(C#N)c2ccc(CC)cc2)cc1OC

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.48
HDAC1 Q13547 4/20 0.41
HDAC2 Q92769 4/20 0.41
MEN1 O00255 2/20 0.40
P2RX7 Q99572 1/20 0.40
ALDH1A1 P00352 3/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
BCHE P06276 1/20 0.39
ACHE P22303 1/20 0.39
KDM4E B2RXH2 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5685372 0.93 KMT2A (0.50) KMT2AHDAC1HDAC2MEN1P2RX7
SCHEMBL5685018 0.93 KMT2A (0.48) KMT2AHDAC1HDAC2MEN1P2RX7
SCHEMBL5686001 0.93 KMT2A (0.48) KMT2AHDAC1HDAC2MEN1P2RX7
SCHEMBL5685043 0.93 KMT2A (0.49) KMT2AHDAC1HDAC2MEN1P2RX7
SCHEMBL5685459 0.92 KMT2A (0.47) KMT2AHDAC1HDAC2MEN1P2RX7
SCHEMBL5687901 0.92 KMT2A (0.47) KMT2AHDAC1HDAC2MEN1P2RX7
SCHEMBL29419114 0.92 KMT2A (0.47) KMT2AHDAC1HDAC2MEN1P2RX7
SCHEMBL68607 0.92 KMT2A (0.47) KMT2AHDAC1HDAC2MEN1P2RX7
SCHEMBL5685528 0.92 KMT2A (0.47) KMT2AHDAC1HDAC2MEN1P2RX7
SCHEMBL5688209 0.92 KMT2A (0.47) KMT2AHDAC1HDAC2MEN1P2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060122064-A1 Amides and method for plant diseases control with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-06-08 US disclosed
EP-1640360-A1 AMIDES AND METHOD FOR PLANT DISEASE CONTROL WITH THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-03-29 EP disclosed
WO-2005122766-A1 FUNGICIDAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-12-29 WO disclosed
EP-1609360-A1 Fungicidal Composition Sumitomo Chemical Company, Limited (JP) 2005-12-28 EP disclosed
US-20050282888-A1 Fungicidal composition SUMITOMO CHEMICAL COMPANY, LIMITED 2005-12-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060122064-A1 Amides and method for plant diseases control with the same ARG1, ARGLU1, ARG2 KMT2A 1374/4885HDAC1 103/4885HDAC2 277/4885
US-20050282888-A1 Fungicidal composition DDT, CYP51A1, DDAH1 KMT2A 445/4885HDAC1 525/4885HDAC2 707/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.