Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6860206 | 0.90 | ALDH1A1 (0.55) | SIGMAR1ALDH1A1SMN1; SMN2TDP1MEN1 | |
| SCHEMBL8912248 | 0.81 | SIGMAR1 (0.60) | SIGMAR1ALDH1A1CHRM5CHRM3SMN1; SMN2 | |
| SCHEMBL7128542 | 0.80 | ALDH1A1 (0.67) | SIGMAR1ALDH1A1SMN1; SMN2TDP1MEN1 | |
| SCHEMBL5550813 | 0.78 | CHRM5 (0.48) | SIGMAR1CHRM5CHRM3HSD17B10 | |
| SCHEMBL12229434 | 0.77 | CHRM5 (0.40) | SIGMAR1CHRM5CHRM3HSD17B10 | |
| SCHEMBL5556374 | 0.77 | CHRM5 (0.47) | SIGMAR1CHRM5CHRM3HSD17B10 | |
| SCHEMBL472213 | 0.76 | CHRM5 (0.50) | SIGMAR1CHRM5CHRM3HSD17B10 | |
| SCHEMBL472190 | 0.76 | CHRM5 (0.50) | SIGMAR1CHRM5CHRM3HSD17B10 | |
| SCHEMBL29299554 | 0.76 | CHRM5 (0.50) | SIGMAR1CHRM5CHRM3HSD17B10 | |
| SCHEMBL306395 | 0.76 | CHRM5 (0.50) | SIGMAR1CHRM5CHRM3HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6719958-B1 | DIAGNOSTIC IMAGING; CONTRAST AGENTS FOR TISSUES OR ORGANS | DIBRA S.P.A. (IT) | 2004-04-13 | — | — | US | disclosed |