Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1411626 | 0.89 | HSD17B10 (0.48) | KMT2AMEN1GPR35HSD17B10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6868421 | 0.87 | HSD17B10 (0.47) | KMT2AMEN1GPR35HSD17B10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9658607 | 0.87 | HSD17B10 (0.47) | KMT2AMEN1GPR35HSD17B10ALDH1A1 | |
| Trifluoromethanesulfonic Acid SCHEMBL11062810 | 0.85 | KMT2A (0.42) | KMT2AMEN1CA1CA2MMP1 | |
| Perchlorate SCHEMBL5573886 | 0.84 | ALDH1A1 (0.46) | KMT2AMEN1GPR35HSD17B10ALDH1A1 | |
| SCHEMBL8043355 | 0.82 | ALDH1A1 (0.44) | KMT2AMEN1CA1CA2MMP1 | |
| SCHEMBL11585259 | 0.82 | ALDH1A1 (0.43) | KMT2AMEN1GPR35HSD17B10ALDH1A1 | |
| SCHEMBL534832 | 0.82 | ALDH1A1 (0.44) | KMT2AMEN1CA1CA2MMP1 | |
| SCHEMBL11224696 | 0.82 | ALDH1A1 (0.44) | KMT2AMEN1GPR35HSD17B10ALDH1A1 | |
| Sulfuric Acid SCHEMBL5646328 | 0.81 | CRHBP (0.49) | KMT2AMEN1CA1CA2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6800676-B2 | ULTRAVIOLET RADIATION ABSORBERS; HEAT AND OXIDATION RESISTANCE | CIBA SPECIALTY CHEMICALS CORPORATION | 2004-10-05 | — | — | US | disclosed |
| EP-1305297-A1 | BENZOTRIAZOLES CONTAINING ALPHA-CUMYL GROUPS SUBSTITUTED BY HETEROATOMS AND COMPOSITIONS STABILIZED THEREWITH | Ciba SC Holding AG (CH) | 2003-05-02 | — | — | EP | disclosed |
| US-20030004235-A1 | Benzotriazoles containing phenyl groups substituted by heteroatoms and compositions stabilized therewith | CIBA SPECIALTY CHEMICALS CORP. | 2003-01-02 | — | — | US | disclosed |
| US-6451887-B1 | Benzotriazoles containing α-cumyl groups substituted by heteroatoms and compositions stabilized therewith | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-09-17 | — | — | US | disclosed |
| EP-1238003-A1 | MONO- AND BIS- BENZOTRIAZOLYLDIHYDROXYBIARYL UV ABSORBERS | CYTEC TECHNOLOGY CORP. (US) | 2002-09-11 | — | — | EP | disclosed |
| WO-2002012205-A1 | BENZOTRIAZOLES CONTAINING α-CUMYL GROUPS SUBSTITUTED BY HETEROATOMS AND COMPOSITIONS STABILIZED THEREWITH | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-02-14 | — | — | WO | disclosed |
| US-6344505-B1 | Mono- and bis-benzotriazolyldihydroxybiaryl UV absorbers | CYTEC INDUSTRIES INC. | 2002-02-05 | — | — | US | disclosed |
| WO-2001034694-A1 | MONO- AND BIS- BENZOTRIAZOLYLDIHYDROXYBIARYL UV ABSORBERS | CYTEC TECHNOLOGY CORP. (US) | 2001-05-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030004235-A1 | Benzotriazoles containing phenyl groups substituted by heteroatoms and compositions stabilized therewith | SUV39H1, SUV39H2, TPST2 | KMT2A 24/4885MEN1 4426/4885CA1 3764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.