Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrrolidine SCHEMBL10413119 | 1.00 | FFAR3 (0.56) | FFAR3ALDH1A1CA2CHKASMN1; SMN2 | |
| Piperidine SCHEMBL1274941 | 1.00 | FFAR3 (0.56) | FFAR3ALDH1A1CA2CHKASMN1; SMN2 | |
| Pyrrolidine SCHEMBL28213560 | 1.00 | FFAR3 (0.56) | FFAR3ALDH1A1CA2CHKASMN1; SMN2 | |
| Piperidine SCHEMBL28047155 | 0.95 | FFAR3 (0.50) | FFAR3ALDH1A1CA2CHKASMN1; SMN2 | |
| Propionic Acid SCHEMBL9615008 | 0.92 | FFAR3 (0.59) | FFAR3ALDH1A1CA2CHKASMN1; SMN2 | |
| Propionic Acid SCHEMBL3790146 | 0.91 | — | — | |
| Piperazine SCHEMBL5818604 | 0.88 | FFAR3 (0.62) | FFAR3ALDH1A1CA2CHKAHDAC3 | |
| Propionic Acid SCHEMBL29104606 | 0.88 | — | — | |
| Piperazine SCHEMBL28214068 | 0.88 | FFAR3 (0.62) | FFAR3ALDH1A1CA2CHKAHDAC3 | |
| Piperidine SCHEMBL28044770 | 0.87 | FFAR3 (0.42) | FFAR3ALDH1A1SMN1; SMN2HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189607-B | Amine-functional polyamides | 建新公司 | 2018-06-15 | — | — | CN | disclosed |
| CN-105189607-A | Amine-functional polyamides | GENZYME CORP | 2015-12-23 | — | — | CN | disclosed |
| EP-0970073-B1 | PROCESS FOR PREPARING EPROSARTAN | SMITHKLINE BEECHAM CORP (US) | 2004-10-27 | — | — | EP | disclosed |
| EP-0970073-A4 | PROCESS FOR PREPARING EPROSARTAN | SMITHKLINE BEECHAM CORP (US) | 2001-01-24 | — | — | EP | disclosed |
| US-6172237-B1 | Process for preparing eprosartan | SMITHKLINE BEECHAM CORPORATION | 2001-01-09 | — | — | US | disclosed |
| EP-0970073-A1 | PROCESS FOR PREPARING EPROSARTAN | SMITHKLINE BEECHAM CORPORATION (US) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998035963-A1 | PROCESS FOR PREPARING EPROSARTAN | SMITHKLINE BEECHAM CORPORATION (US) | 1998-08-20 | — | — | WO | disclosed |