Piperidine

Piperidine

SCHEMBL1274941

C1CCNCC1.CCC(=O)O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 2/20 0.56
ALDH1A1 P00352 2/20 0.50
CA2 P00918 1/20 0.36
CHKA P35790 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
CXCR4 P61073 1/20 0.35
HDAC3 O15379 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
GABRA5 P31644 3/20 0.35
GABRB2 P47870 3/20 0.35
TSHR P16473 2/20 0.35
GABRA1 P14867 2/20 0.35
GABRA4 P48169 2/20 0.35
GABRP O00591 1/20 0.35
GABRD O14764 1/20 0.35
GABRB1 P18505 1/20 0.35
GABRG2 P18507 1/20 0.35
GABRB3 P28472 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrrolidine SCHEMBL10413119 1.00 FFAR3 (0.56) FFAR3ALDH1A1CA2CHKASMN1; SMN2
Piperidine SCHEMBL6861563 1.00 FFAR3 (0.56) FFAR3ALDH1A1CA2CHKASMN1; SMN2
Pyrrolidine SCHEMBL28213560 1.00 FFAR3 (0.56) FFAR3ALDH1A1CA2CHKASMN1; SMN2
Piperidine SCHEMBL28047155 0.95 FFAR3 (0.50) FFAR3ALDH1A1CA2CHKASMN1; SMN2
Propionic Acid SCHEMBL9615008 0.92 FFAR3 (0.59) FFAR3ALDH1A1CA2CHKASMN1; SMN2
Propionic Acid SCHEMBL3790146 0.91
Piperazine SCHEMBL5818604 0.88 FFAR3 (0.62) FFAR3ALDH1A1CA2CHKAHDAC3
Propionic Acid SCHEMBL29104606 0.88
Piperazine SCHEMBL28214068 0.88 FFAR3 (0.62) FFAR3ALDH1A1CA2CHKAHDAC3
Piperidine SCHEMBL28044770 0.87 FFAR3 (0.42) FFAR3ALDH1A1SMN1; SMN2HDAC3HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024219260-A1 BEAUTY TREATMENT METHOD, METHOD FOR PROMOTING PERCUTANEOUS PENETRATION, AND BEAUTY TREATMENT KIT 株式会社 資生堂 2024-10-24 WO claimed
US-20240293300-A1 SKIN PENETRATION COSMETIC MATERIAL, AND SKIN PENETRATION COSMETIC MATERIAL PRODUCTION METHOD SHISEIDO COMPANY, LTD. (JP) 2024-09-05 US claimed
WO-2023002873-A1 SKIN PENETRATION COSMETIC MATERIAL, AND SKIN PENETRATION COSMETIC MATERIAL PRODUCTION METHOD 株式会社資生堂 2023-01-26 WO claimed
CN-110128136-B Anti-static ceramic material and preparation method thereof 亚细亚新材料科技股份公司 2022-04-19 CN claimed
CN-110128136-A A kind of anti-electrostatic ceramic material and preparation method thereof 谢红兵 2019-08-16 CN claimed
EP-1699753-B1 IMPROVED PROCESS FOR THE PREPARATION OF ENTACAPONE SUVEN LIFE SCIENCES LTD (IN) 2014-11-26 EP claimed
CN-1906183-B N-acylsulfonamide apoptosis promoters ABBOTT LAB 2012-06-20 CN claimed
US-20110054186-A1 PROCESS FOR EPROSARTAN INTERMEDIATE HETERO RESEARCH FOUNDATION (IN) 2011-03-03 US claimed
EP-2257540-A2 IMPROVED PROCESS FOR EPROSARTAN INTERMEDIATE Hetero Research Foundation (IN) 2010-12-08 EP claimed
US-20100234632-A1 PROCESS FOR THE PREPARATION OF ENTACAPONE ALEMBIC LIMITED 2010-09-16 US claimed
EP-1699753-A1 IMPROVED PROCESS FOR THE PREPARATION OF ENTACAPONE Suven Life Sciences Limited (IN) 2006-09-13 EP claimed
CN-1249039-C Inhibitors of 11 beta-hydroxysteroid dehydrogenase type I BIOVITRUM AB (SE) 2006-04-05 CN claimed
WO-2005063693-A1 IMPROVED PROCESS FOR THE PREPARATION OF ENTACAPONE SUVEN LIFE SCIENCES LTD (IN) 2005-07-14 WO claimed
EP-0970073-B1 PROCESS FOR PREPARING EPROSARTAN SMITHKLINE BEECHAM CORP (US) 2004-10-27 EP claimed
CN-1438997-A Inhibitors of 11-beta-hydroxy steroid dehydrogenase type I BIOVITRUM AB (SE) 2003-08-27 CN claimed
CN-1290165-A Benzothiazole Protein tyrosine kinase inhibitors BRISTOL MYERS SQUIBB CO (US) 2001-04-04 CN claimed
EP-0970073-A4 PROCESS FOR PREPARING EPROSARTAN SMITHKLINE BEECHAM CORP (US) 2001-01-24 EP claimed
US-6172237-B1 Process for preparing eprosartan SMITHKLINE BEECHAM CORPORATION 2001-01-09 US claimed
EP-0970073-A1 PROCESS FOR PREPARING EPROSARTAN SMITHKLINE BEECHAM CORPORATION (US) 2000-01-12 EP claimed
WO-1998035963-A1 PROCESS FOR PREPARING EPROSARTAN SMITHKLINE BEECHAM CORPORATION (US) 1998-08-20 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110054186-A1 PROCESS FOR EPROSARTAN INTERMEDIATE PTGER1, PTGER4, PDGFRA FFAR3 28/4885ALDH1A1 761/4885CA2 3144/4885
US-20240293300-A1 SKIN PENETRATION COSMETIC MATERIAL, AND SKIN PENETRATION COSMETIC MATERIAL PRODUCTION METHOD CUTA, SLC6A12, DSG1 FFAR3 2703/4885ALDH1A1 1185/4885CA2 3587/4885
US-20100234632-A1 PROCESS FOR THE PREPARATION OF ENTACAPONE DDC, GNE, GNPAT FFAR3 3631/4885ALDH1A1 37/4885CA2 1881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.