Piperidine

Piperidine

SCHEMBL28044770

C1CCNCC1.CCC(=O)O.CCC(=O)O.NCCCN

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.42
LMNA P02545 3/20 0.39
BLM P54132 3/20 0.39
CYP1A2 P05177 3/20 0.39
THRB P10828 2/20 0.39
KMT2A Q03164 2/20 0.39
NPSR1 Q6W5P4 2/20 0.39
TSHR P16473 2/20 0.39
GABRR3 A8MPY1 1/20 0.39
GABRP O00591 1/20 0.39
GABRD O14764 1/20 0.39
HDAC3 O15379 1/20 0.39
GABBR2 O75899 1/20 0.39
GABRA1 P14867 1/20 0.39
GABRB1 P18505 1/20 0.39
GABRG2 P18507 1/20 0.39
GABRR1 P24046 1/20 0.39
GABRB3 P28472 1/20 0.39
GABRR2 P28476 1/20 0.39
SLC6A1 P30531 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Piperidine SCHEMBL6861563 0.87 FFAR3 (0.56) FFAR3LMNATSHRGABRPGABRD
Piperidine SCHEMBL1274941 0.87 FFAR3 (0.56) FFAR3LMNATSHRGABRPGABRD
Pyrrolidine SCHEMBL10413119 0.87 FFAR3 (0.56) FFAR3LMNATSHRGABRPGABRD
Pyrrolidine SCHEMBL28213560 0.87 FFAR3 (0.56) FFAR3LMNATSHRGABRPGABRD
Piperidine SCHEMBL28047155 0.82 FFAR3 (0.50) FFAR3LMNAKMT2ATSHRGABRP
Propionic Acid SCHEMBL28047136 0.82 FFAR3 (0.62) FFAR3LMNABLMCYP1A2THRB
Propionic Acid SCHEMBL14342961 0.82 FFAR3 (0.62) FFAR3LMNABLMCYP1A2THRB
Aminocaproic Acid SCHEMBL4631221 0.80 LMNA (0.65) LMNABLMCYP1A2THRBKMT2A
Piperidine SCHEMBL28044758 0.80 GABRR1 (0.43) FFAR3LMNAGABBR2GABRR1GABBR1
Piperidine SCHEMBL1820163 0.80 GLRA1 (0.53) FFAR3LMNABLMCYP1A2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105189607-B Amine-functional polyamides 建新公司 2018-06-15 CN disclosed
CN-105189607-A Amine-functional polyamides GENZYME CORP 2015-12-23 CN disclosed