SCHEMBL6861652

SCHEMBL6861652

[c]1cccc(Cc2ccccn2)n1

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.44
HRH3 Q9Y5N1 2/20 0.43
HRH1 P35367 2/20 0.42
HRH4 Q9H3N8 1/20 0.42
LMNA P02545 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42
ALDH1A1 P00352 1/20 0.42
ALOX15 P16050 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
MAPT P10636 1/20 0.41
LIN28A Q9H9Z2 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
ASIC3 Q9UHC3 1/20 0.41
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL41191 0.81 L3MBTL1 (0.59) L3MBTL1HRH3HRH1HRH4LMNA
SCHEMBL29830938 0.81 L3MBTL1 (0.59) L3MBTL1HRH3HRH1HRH4LMNA
SCHEMBL29715188 0.79 L3MBTL1 (0.57) L3MBTL1HRH3HRH1HRH4LMNA
SCHEMBL4938201 0.79 L3MBTL1 (0.57) L3MBTL1HRH3HRH1HRH4LMNA
SCHEMBL4938207 0.79 L3MBTL1 (0.57) L3MBTL1HRH3HRH1HRH4LMNA
Ammonia Solution, Strong SCHEMBL6176560 0.79 L3MBTL1 (0.57) L3MBTL1HRH3HRH1HRH4LMNA
Hydrochloric Acid SCHEMBL10884973 0.79 L3MBTL1 (0.57) L3MBTL1HRH3HRH1HRH4LMNA
Bromide SCHEMBL6114859 0.79 L3MBTL1 (0.57) L3MBTL1HRH3HRH1HRH4LMNA
SCHEMBL3587955 0.76 CALM1 (0.44) L3MBTL1HRH3TAAR1ALDH1A1SMN1; SMN2
SCHEMBL6167420 0.73 L3MBTL1 (0.44) L3MBTL1HRH3HRH1HRH4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1238338-C Process for the preparation of 4(5)-amino-5(4)carboxamidoimidoimidazoles and intermediates thereof NIPPON SODA CO (JP) 2006-01-25 CN disclosed
US-6797828-B1 Processes for the preparation of 4(5)-amino-5(4)-carboxamidoimidazoles and intermediates thereof NIPPON SODA CO. LTD. (JP) 2004-09-28 US disclosed
CN-1502604-A Process for the preparation of 4(5)-amino-5(4)carboxamidoimidoimidazoles and intermediates thereof �ձ�������ʽ���� 2004-06-09 CN disclosed
CN-1150169-C Process for the preparation of 4(5) -amino-5 (4) -carbamoylimidazoles and intermediates thereof �ձ�������ʽ���� 2004-05-19 CN disclosed
CN-1374951-A Process for the preparation of 4(5) -amino-5 (4) -carbamoylimidazoles and intermediates thereof NIPPON SODA CO (JP) 2002-10-16 CN disclosed
EP-1215206-A1 PROCESSES FOR THE PREPARATION OF 4(5)-AMINO-5(4)-CARBOXAMIDOIMIDAZOLES AND INTERMEDIATES THEREOF NIPPON SODA CO., LTD. (JP) 2002-06-19 EP disclosed