Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CD74 | P04233 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6543577 | 0.82 | ESR1 (0.46) | L3MBTL1RAB9ATAAR1CD74MIF | |
| SCHEMBL1202201 | 0.82 | KCNH2 (0.55) | ALDH1A1SMN1; SMN2TDP1KCNH2MAOB | |
| SCHEMBL28447286 | 0.77 | TSHR (0.54) | L3MBTL1RAB9ASMN1; SMN2KCNH2MAOB | |
| SCHEMBL6861652 | 0.76 | L3MBTL1 (0.44) | ALDH1A1L3MBTL1SMN1; SMN2TDP1MAOB | |
| SCHEMBL1517986 | 0.74 | BRD4 (0.39) | CALM1ALDH1A1L3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL6544806 | 0.73 | SHBG (0.39) | ALDH1A1POLB | |
| SCHEMBL8649366 | 0.72 | CALM1 (0.41) | CALM1L3MBTL1TAAR1HTR2CHRH3 | |
| SCHEMBL1809188 | 0.71 | — | — | |
| SCHEMBL11330543 | 0.70 | KCNH2 (0.62) | CALM1ALDH1A1L3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL1240393 | 0.69 | CALM1 (0.42) | CALM1ALDH1A1L3MBTL1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014121036-A1 | 5-DEUTERO-2,4-THIAZOLIDINEDIONE AND 5-DEUTERO-2,4-OXAZOLIDINEDIONE DERIVATIVES AND COMPOSITIONS COMPRISING AND METHODS OF USING THE SAME | DEUTERX, LLC (US) | 2014-08-07 | — | — | WO | disclosed |
| US-20140221369-A1 | 5-DEUTERO-2,4-THIAZOLIDINEDIONE AND 5-DEUTERO-2,4-OXAZOLIDINEDIONE DERIVATIVES AND COMPOSITIONS COMPRISING AND METHODS OF USING THE SAME | DEUTERX, LLC (US) | 2014-08-07 | — | — | US | disclosed |
| CN-101372521-B | Copolymers of ethylene with alpha-olefins | BASELL POLYOLEFINE GMBH | 2011-09-07 | — | — | CN | disclosed |
| US-20100022559-A1 | BISOXIMES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2010-01-28 | — | — | US | disclosed |
| US-7534847-B2 | Copolymers of ethylene with α-olefins | BASELL POLYOLEFINE GMBH (DE) | 2009-05-19 | — | — | US | disclosed |
| CN-101372521-A | Copolymers of ethylene with alpha-olefins | BASELL POLYOLEFINE GMBH (DE) | 2009-02-25 | — | — | CN | disclosed |
| CN-100406475-C | Copolymers of ethylene and alpha-olefins | BASELL POLYOLEFINE GMBH (DE) | 2008-07-30 | — | — | CN | disclosed |
| CN-1255386-C | Substituted fused heterocyclic compound | SANKYO CO (JP) | 2006-05-10 | — | — | CN | disclosed |
| CN-1729210-A | Copolymers of ethylene and alpha-olefins | BASELL POLYOLEFINE GMBH (DE) | 2006-02-01 | — | — | CN | disclosed |
| US-20050282979-A1 | Copolymers of ethylene with alpha-olefins | BASELL POLYOLEFINE GMBH (DE) | 2005-12-22 | — | — | US | disclosed |
| CN-1280570-A | Substituted fused heterocyclic compounds | SANKYO CO (JP) | 2001-01-17 | — | — | CN | disclosed |
| EP-1022272-A1 | SUBSTITUTED FUSED HETEROCYCLIC COMPOUNDS | Sankyo Company Limited (JP) | 2000-07-26 | — | — | EP | disclosed |
| CN-1161687-A | Phenylacetic acid alkyl esters | BASF AG (DE) | 1997-10-08 | — | — | CN | disclosed |
| US-5554578-A | Oxime ether derivatives, their preparation and fungicides containing these derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1996-09-10 | — | — | US | disclosed |
| US-5468717-A | Oxime ether derivatives, their preparation and fungicides containing these derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1995-11-21 | — | — | US | disclosed |
| US-5378711-A | α-arylacrylates substituted by a heterocyclic radical, and fungicides which contain these compounds | BASF AKTIENGESELLSCHAFT (DE) | 1995-01-03 | — | — | US | disclosed |
| US-5334577-A | 2-(substituted pyridy-oxymethyl)-phenylglyoxylate alkyloxime | BASF AKTIENGESELLSCHAFT (DE) | 1994-08-02 | — | — | US | disclosed |
| US-5326767-A | α-arylacrylates substituted by a heterocyclic radical, and fungicides which contain these compounds | BASF AKTIENGESELLSCHAFT (DE) | 1994-07-05 | — | — | US | disclosed |
| US-5286750-A | For crops or ornamental plants | BASF AKTIENGESELLSCHAFT (DE) | 1994-02-15 | — | — | US | disclosed |
| US-5157037-A | α-arylacrylates substituted by a heterocyclic radical, and fungicides which contain these compounds | BASF AKTIENGESELLSCHAFT (DE) | 1992-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221369-A1 | 5-DEUTERO-2,4-THIAZOLIDINEDIONE AND 5-DEUTERO-2,4-OXAZOLIDINEDIONE DERIVATIVES AND COMPOSITIONS COMPRISING AND METHODS OF USING THE SAME | SRD5A2, PPARD, SRD5A1 | CALM1 4320/4885ALDH1A1 963/4885L3MBTL1 3954/4885 |
| US-20100022559-A1 | BISOXIMES AS FUNGICIDES | DDT, FHIT, CYP4X1 | CALM1 3859/4885ALDH1A1 2634/4885L3MBTL1 1024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.