Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ADH1B | P00325 | 3/20 | 0.34 |
| ▸ | ADH1C | P00326 | 3/20 | 0.34 |
| ▸ | ADH1A | P07327 | 3/20 | 0.34 |
| ▸ | ADH7 | P40394 | 3/20 | 0.34 |
| ▸ | ADH4 | P08319 | 2/20 | 0.34 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1782481 | 0.80 | TSHR (0.52) | TSHRFAAHTRPV1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1410276 | 0.80 | TSHR (0.59) | TSHRFAAHTRPV1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1781742 | 0.80 | TSHR (0.52) | TSHRFAAHTRPV1SMN1; SMN2ALDH1A1 | |
| SCHEMBL28389299 | 0.80 | TSHR (0.48) | TSHRFAAHTRPV1SMN1; SMN2ALDH1A1 | |
| SCHEMBL31521583 | 0.77 | DNM1 (0.38) | TSHRSMN1; SMN2ALDH1A1CYP3A4FDPS | |
| SCHEMBL5360967 | 0.76 | TSHR (0.56) | TSHRFAAHTRPV1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1782669 | 0.76 | TSHR (0.46) | TSHRFAAHTRPV1SMN1; SMN2ALDH1A1 | |
| SCHEMBL28074616 | 0.75 | DNM1 (0.48) | TSHRADH1BADH1CADH1AADH7 | |
| SCHEMBL1784414 | 0.75 | HIF1A (0.45) | TSHRFAAHTRPV1ALDH1A1HIF1A | |
| SCHEMBL812757 | 0.74 | TSHR (0.52) | TSHRFAAHTRPV1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6835218-B1 | For sustained release in automobiles, trucks, and heavy equipment | DOBER CHEMICAL CORP. | 2004-12-28 | — | — | US | disclosed |
| WO-2003018727-A1 | FUEL ADDITIVE COMPOSITIONS | DOBER CHEMICAL CORPORATION (US) | 2003-03-06 | — | — | WO | disclosed |