Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1783246 | 0.93 | TSHR (0.46) | TSHRHIF1AFAAHTRPV1ALDH1A1 | |
| SCHEMBL1782481 | 0.86 | TSHR (0.52) | TSHRHIF1AFAAHTRPV1ALDH1A1 | |
| SCHEMBL1787215 | 0.85 | ALDH1A1 (0.41) | TSHRHIF1AFAAHTRPV1ALDH1A1 | |
| SCHEMBL1784414 | 0.80 | HIF1A (0.45) | TSHRHIF1AFAAHTRPV1ALDH1A1 | |
| SCHEMBL17143811 | 0.78 | — | — | |
| SCHEMBL231192 | 0.78 | — | — | |
| SCHEMBL1781742 | 0.76 | TSHR (0.52) | TSHRHIF1AFAAHTRPV1ALDH1A1 | |
| SCHEMBL29273148 | 0.76 | TSHR (0.46) | TSHRHIF1AFAAHTRPV1ALDH1A1 | |
| SCHEMBL6861914 | 0.76 | TSHR (0.52) | TSHRHIF1AFAAHTRPV1ALDH1A1 | |
| SCHEMBL11765070 | 0.76 | LMNA (0.31) | TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8632792-B2 | Cooling sensation agent composition and sensory stimulation agent composition | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2014-01-21 | — | — | US | disclosed |
| CN-101583587-B | Process for preparing polyalcohols from formaldehyde with a low formic acid content | BASF SE | 2012-08-08 | — | — | CN | disclosed |
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-05-19 | — | — | US | disclosed |
| CN-101583587-A | Process for preparing polyalcohols from formaldehyde with a low formic acid content | BASF SE (DE) | 2009-11-18 | — | — | CN | disclosed |
| WO-2009123355-A2 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-10-08 | — | — | WO | disclosed |
| US-7462747-B2 | of by-products can advantageously be prevented in a targeted manner and the yield of the desired polymethylol compound can thereby be increased; condensing an aldehyde with formaldehyde in an aldol reaction to form an alkanal, hydrogenating the alkanal | BASF AKTIENGESELLSCHAFT (DE) | 2008-12-09 | — | — | US | disclosed |
| US-20080167506-A1 | of by-products can advantageously be prevented in a targeted manner and the yield of the desired polymethylol compound can thereby be increased; condensing an aldehyde with formaldehyde in an aldol reaction to form an alkanal, hydrogenating the alkanal | BASF AKTIENGESELLSCHAFT (DE) | 2008-07-10 | — | — | US | disclosed |
| US-7186782-B2 | Hydrogenation catalyst composition and process for hydrogenation of conjugated diene polymer | TSRC CORPORATION (TW) | 2007-03-06 | — | — | US | disclosed |
| US-20060041079-A1 | Hydrogenation catalyst composition and process for hydrogenation of conjugated diene polymer | TSRC CORPORATION | 2006-02-23 | — | — | US | disclosed |
| US-6881797-B2 | Process for hydrogenation of conjugated diene polymer | TSRC CORPORATION (TW) | 2005-04-19 | — | — | US | disclosed |
| US-20040082727-A1 | Process for hydrogenation of conjugated diene polymer | TSRC CORPORATION (CN) | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080167506-A1 | of by-products can advantageously be prevented in a targeted manner and the yield of the desired polymethylol compound can thereby be increased; condensing an aldehyde with formaldehyde in an aldol reaction to form an alkanal, hydrogenating the alkanal | ASH2L, AKR7A2, HACL2 | TSHR 4634/4885HIF1A 1662/4885FAAH 106/4885 |
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TRPA1, HRH1, HRH2 | TSHR 2479/4885HIF1A 1980/4885FAAH 94/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.