Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | EGFR | P00533 | 4/20 | 0.58 |
| ▸ | SRC | P12931 | 2/20 | 0.58 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | GPR17 | Q13304 | 3/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30479097 | 1.00 | KDM4E (0.63) | KDM4EALDH1A1EGFRSRCOXER1 | |
| SCHEMBL6014774 | 0.87 | KDM4E (0.61) | KDM4EALDH1A1EGFRSRCOXER1 | |
| SCHEMBL6865930 | 0.84 | ALOX5 (0.56) | KDM4EALDH1A1EGFRSRCOXER1 | |
| SCHEMBL29127032 | 0.80 | ALDH1A1 (0.58) | KDM4EALDH1A1EGFRSRCOXER1 | |
| SCHEMBL2944735 | 0.80 | MTNR1A (0.66) | KDM4EALDH1A1EGFRSRCMEN1 | |
| SCHEMBL27348910 | 0.79 | EGFR (0.63) | KDM4EALDH1A1EGFRSRCOXER1 | |
| SCHEMBL29432490 | 0.78 | KDM4E (1.00) | KDM4EALDH1A1EGFRSRCGPR17 | |
| SCHEMBL7551694 | 0.78 | OXER1 (0.60) | KDM4EALDH1A1OXER1KMT2ATDP1 | |
| SCHEMBL9188195 | 0.78 | KDM4E (1.00) | KDM4EALDH1A1EGFRSRCGPR17 | |
| SCHEMBL28516422 | 0.77 | KDM4E (0.66) | KDM4EALDH1A1EGFRSRCMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023185709-A1 | MARKER COMBINATION FOR DIAGNOSING ADVANCED COLORECTAL TUMOR, AND APPLICATION THEREOF | 武汉迈特维尔医学科技有限公司 | 2023-10-05 | — | — | WO | claimed |
| CN-116430047-A | Metabolic marker for evaluating colorectal cancer and colorectal cancer risk in progressive stage and application thereof | 武汉迈特维尔医学科技有限公司 | 2023-07-14 | — | — | CN | claimed |
| WO-2023185709-A1 | MARKER COMBINATION FOR DIAGNOSING ADVANCED COLORECTAL TUMOR, AND APPLICATION THEREOF | 武汉迈特维尔医学科技有限公司 | 2023-10-05 | — | — | WO | disclosed |
| CN-116430047-A | Metabolic marker for evaluating colorectal cancer and colorectal cancer risk in progressive stage and application thereof | 武汉迈特维尔医学科技有限公司 | 2023-07-14 | — | — | CN | disclosed |
| US-20040053911-A1 | Substituted bis-indole derivatives useful as contrast agents, pharmaceutical compositions containing them and intermediates for producing them | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2004-03-18 | — | — | US | disclosed |
| EP-1343758-A1 | SUBSTITUTED BIS-INDOLE DERIVATIVES USEFUL AS CONTRAST AGENTS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND INTERMEDIATES FOR PRODUCING THEM | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002038546-A1 | SUBSTITUTED BIS-INDOLE DERIVATIVES USEFUL AS CONTRAST AGENTS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND INTERMEDIATES FOR PRODUCING THEM | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2002-05-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040053911-A1 | Substituted bis-indole derivatives useful as contrast agents, pharmaceutical compositions containing them and intermediates for producing them | IDO1, IDO2, CNR1 | KDM4E 3436/4885ALDH1A1 1910/4885EGFR 3859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.