Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6860667 | 0.87 | LMNA (0.44) | POLBTP53GAARAB9AMAPT | |
| SCHEMBL6860631 | 0.84 | OPRD1 (0.43) | POLBMAPTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL6860642 | 0.84 | SMN1; SMN2 (0.49) | POLBTP53GAAMAPTSMN1; SMN2 | |
| SCHEMBL1007201 | 0.73 | POLB (0.56) | POLBTP53GAAMAPTSMN1; SMN2 | |
| SCHEMBL16832447 | 0.73 | GAA (0.54) | POLBGAARAB9ASMN1; SMN2FAAH | |
| SCHEMBL26923626 | 0.71 | CHKA (0.42) | POLBTP53GAARAB9ASMN1; SMN2 | |
| SCHEMBL1009404 | 0.71 | SMN1; SMN2 (0.55) | POLBTP53GAAMAPTSMN1; SMN2 | |
| SCHEMBL13773366 | 0.71 | MAPT (0.69) | POLBTP53GAAMAPTSMN1; SMN2 | |
| SCHEMBL1897157 | 0.71 | MAPT (0.75) | POLBTP53GAAMAPTSMN1; SMN2 | |
| SCHEMBL1006480 | 0.71 | POLB (0.53) | POLBTP53GAAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011036889-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2011-03-31 | — | — | WO | disclosed |