Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.75 |
| ▸ | TP53 | P04637 | 4/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.72 |
| ▸ | MEN1 | O00255 | 5/20 | 0.72 |
| ▸ | THRB | P10828 | 1/20 | 0.72 |
| ▸ | ESR1 | P03372 | 6/20 | 0.69 |
| ▸ | STS | P08842 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 8/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.64 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.63 |
| ▸ | ATM | Q13315 | 3/20 | 0.63 |
| ▸ | PGR | P06401 | 3/20 | 0.63 |
| ▸ | AR | P10275 | 3/20 | 0.63 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.63 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10327706 | 0.90 | LMNA (0.79) | MAPTCYP3A4SMN1; SMN2TP53KMT2A | |
| SCHEMBL10328159 | 0.88 | LMNA (0.81) | MAPTCYP3A4SMN1; SMN2TP53KMT2A | |
| SCHEMBL17302844 | 0.86 | MAPT (1.00) | MAPTCYP3A4SMN1; SMN2TP53KMT2A | |
| SCHEMBL14094308 | 0.86 | MAPT (1.00) | MAPTCYP3A4SMN1; SMN2TP53KMT2A | |
| SCHEMBL147461 | 0.86 | MAPT (1.00) | MAPTCYP3A4SMN1; SMN2TP53KMT2A | |
| SCHEMBL29616163 | 0.86 | MAPT (1.00) | MAPTCYP3A4SMN1; SMN2TP53KMT2A | |
| SCHEMBL29351015 | 0.86 | MAPT (1.00) | MAPTCYP3A4SMN1; SMN2TP53KMT2A | |
| SCHEMBL11846415 | 0.85 | ESR1 (0.79) | MAPTCYP3A4SMN1; SMN2TP53KMT2A | |
| SCHEMBL10360572 | 0.84 | ESR1 (0.58) | MAPTCYP3A4SMN1; SMN2TP53KMT2A | |
| Estradiol Dipropionate SCHEMBL23262384 | 0.83 | MAPT (1.00) | MAPTCYP3A4SMN1; SMN2TP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6794384-B1 | Hydroxylation activated drug release | DE MONTFORT UNIVERSITY (GB) | 2004-09-21 | — | — | US | disclosed |
| EP-1069915-B1 | HYDROXYLATION ACTIVATED DRUG RELEASE | UNIV MONTFORT (GB) | 2003-06-25 | — | — | EP | disclosed |
| US-20020037296-A1 | HYDROXYLATION ACTIVATED DRUG RELEASE | SPEAR THERAPEUTICS LIMITED (GB) | 2002-03-28 | — | — | US | disclosed |
| EP-1069915-A2 | HYDROXYLATION ACTIVATED DRUG RELEASE | DE MONTFORT UNIVERSITY (GB) | 2001-01-24 | — | — | EP | disclosed |
| WO-1999040944-A2 | HYDROXYLATION ACTIVATED DRUG RELEASE | DE MONTFORT UNIVERSITY (GB) | 1999-08-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020037296-A1 | HYDROXYLATION ACTIVATED DRUG RELEASE | CYP1A1, CYP1B1, CYP1A2 | MAPT 4276/4885CYP3A4 9/4885SMN1; SMN2 4775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.