Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711735 | 0.83 | NPC1 (0.49) | PARP1KMT2AMEN1L3MBTL1NPC1 | |
| SCHEMBL9711621 | 0.83 | PARP1 (0.42) | PARP1KMT2AMEN1OPRM1OPRK1 | |
| SCHEMBL9711757 | 0.82 | RAB9A (0.44) | NPC1RAB9A | |
| SCHEMBL8466743 | 0.82 | MAPT (0.49) | LMNAL3MBTL1NPC1RAB9APKM | |
| SCHEMBL9711527 | 0.81 | KMO (0.47) | KMT2AMEN1LMNAOPRM1OPRD1 | |
| SCHEMBL9711491 | 0.80 | CES2 (0.49) | KMT2AMEN1LMNANPSR1 | |
| SCHEMBL9711489 | 0.79 | CES2 (0.50) | KMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL9711460 | 0.77 | ALDH1A1 (0.44) | PARP1KMT2AMEN1LMNANPC1 | |
| SCHEMBL9711583 | 0.77 | SMN1; SMN2 (0.44) | PARP1KMT2AMEN1L3MBTL1NPC1 | |
| SCHEMBL9711601 | 0.77 | HSD11B1 (0.44) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114461-A | Herbicides | MAY & BAKER LIMITED (GB) | 1992-05-19 | — | — | US | disclosed |
| EP-0278742-A2 | Cyclic diones | MAY & BAKER LIMITED (GB) | 1988-08-17 | — | — | EP | disclosed |