Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL29048893 | 0.96 | CYP1A2 (0.39) | CYP1A2ALOX5CYP2A6TYRSMN1; SMN2 | |
| SCHEMBL9680746 | 0.94 | ALDH1A1 (0.39) | CYP1A2ALOX5CYP2A6TYRSMN1; SMN2 | |
| Ethylene Glycol SCHEMBL29048889 | 0.90 | CYP1A2 (0.40) | CYP1A2ALOX5SMN1; SMN2CYP2C19PYCR1 | |
| SCHEMBL21628043 | 0.87 | TYR (0.46) | TYR | |
| SCHEMBL11442832 | 0.84 | LMNA (0.40) | ALOX5LMNA | |
| SCHEMBL29595346 | 0.80 | TYR (0.41) | TYR | |
| SCHEMBL454717 | 0.80 | TYR (0.58) | TYRALDH1A1POLBLMNA | |
| SCHEMBL874206 | 0.80 | TYR (0.58) | TYRALDH1A1POLBLMNA | |
| SCHEMBL4831627 | 0.78 | CYP2A6 (0.44) | ALOX5CYP2A6TYRSMN1; SMN2ALDH1A1 | |
| Methane SCHEMBL28983045 | 0.78 | TYR (0.56) | TYRSMN1; SMN2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114956932-B | Synthesis method of polysubstituted chiral tetrahydroquinoline compound | 东北大学秦皇岛分校 | 2023-11-10 | — | — | CN | claimed |
| CN-114956932-A | Synthesis method of polysubstituted chiral tetrahydroquinoline compound | 东北大学秦皇岛分校 | 2022-08-30 | — | — | CN | claimed |
| CN-112811994-B | Difluoro ether compound with 3-pentenyl end group and synthesis method thereof | 江苏和成新材料有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-114956932-B | Synthesis method of polysubstituted chiral tetrahydroquinoline compound | 东北大学秦皇岛分校 | 2023-11-10 | — | — | CN | disclosed |
| CN-113845442-B | Method for preparing p-bromobenzonitrile | 孙国伟 | 2023-09-29 | — | — | CN | disclosed |
| CN-115536511-B | 1, 4-dialdehyde ketone compound, synthesis method and application thereof | 徐州医科大学 | 2023-08-22 | — | — | CN | disclosed |
| CN-116332929-A | 3-amido-beta-carboline compound, preparation method and application thereof | 中国科学院上海药物研究所 | 2023-06-27 | — | — | CN | disclosed |
| CN-110128298-A | The synthetic method of one seed sand library Ba Qu intermediate | 南京一心和医药科技有限公司 | 2019-08-16 | — | — | CN | disclosed |
| CN-109081830-A | Benzimidazole substituted diphenyl pyrimidine compound and organic electroluminescent device thereof | 昱镭光电科技股份有限公司 | 2018-12-25 | — | — | CN | disclosed |
| CN-107567443-A | biaryl derivatives as GPR120 agonists | 株式会社LG化学 | 2018-01-09 | — | — | CN | disclosed |
| CN-107205391-A | Histone demethylase inhibitors | 赛尔基因昆蒂赛尔研究公司 | 2017-09-26 | — | — | CN | disclosed |
| US-5136013-A | Polyesters | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-04 | — | — | US | disclosed |
| US-5068300-A | BIFUNCTIONAL STILBENE COMPOUNDS CONTAINING AT LEAST ONE Z-CONFIGURATED STILBENE GROUP, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR THE PREPARATION OF POLYMERS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-11-26 | — | — | US | disclosed |
| US-4417052-A | ANTIINFLAMMATORY AGENTS; ANALGESICS; VIRICIDES | STERLING DRUG INC. (US) | 1983-11-22 | — | — | US | disclosed |
| US-4396765-A | ANTIASTHMATICS, BRONCHODILATORS | STERLING DRUG INC. (US) | 1983-08-02 | — | — | US | disclosed |
| US-4339576-A | Anti-asthmatic, anti-allergic, anti-cholinergic, bronchodilator and anti-inflammatory 1-[(benzoylphenyl)-lower-alkyl]piperidines and analogs thereof | STERLING DRUG INC. (US) | 1982-07-13 | — | — | US | disclosed |
| EP-0052311-A1 | 1-((Benzoylphenyl) - lower-alkyl) piperidines and carbinol analogs and preparation thereof | STERLING DRUG INC. (US) | 1982-05-26 | — | — | EP | disclosed |
| US-4308382-A | ANTIINFLAMMATORY AGENTS | STERLING DRUG INC. (US) | 1981-12-29 | — | — | US | disclosed |
| US-4304911-A | ANTIHISTAMINES, ANTIALLERGENS, ANTICHOLINERGIC AGENTS, ANTIINFLAMMATORY AGENTS, BRONCHODILATOR AGENTS, AND ANALGESICS | STERLING DRUG INC. (US) | 1981-12-08 | — | — | US | disclosed |
| US-4216326-A | Intermediates for preparing anti-inflammatory phenyl-lower-alkylamines | STERLING DRUG INC. (US) | 1980-08-05 | — | — | US | disclosed |