Ethylene Glycol

Ethylene Glycol

SCHEMBL29048889

CC(C=O)c1ccc(Br)cc1.OCCO

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.40
ALOX5 P09917 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.37
CYP2C19 P33261 1/20 0.36
PYCR1 P32322 1/20 0.35
POLB P06746 1/20 0.35
ALDH1A1 P00352 1/20 0.35
TRPA1 O75762 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL686436 0.90 CYP1A2 (0.42) CYP1A2ALOX5SMN1; SMN2CYP2C19PYCR1
Ethylene SCHEMBL29048893 0.86 CYP1A2 (0.39) CYP1A2ALOX5SMN1; SMN2CYP2C19PYCR1
SCHEMBL9680746 0.84 ALDH1A1 (0.39) CYP1A2ALOX5SMN1; SMN2CYP2C19PYCR1
SCHEMBL11442832 0.79 LMNA (0.40) ALOX5
SCHEMBL21628043 0.78 TYR (0.46) TRPA1
SCHEMBL27633563 0.76 CA12 (0.36) ALOX5TRPA1
SCHEMBL10936542 0.73 NR1I2 (0.46) SMN1; SMN2ALDH1A1
SCHEMBL351626 0.73 ESR1 (0.54) CYP1A2SMN1; SMN2CYP2C19ALDH1A1
SCHEMBL27791171 0.72 TSHR (0.36) ALOX5ALDH1A1TRPA1
Alcohol SCHEMBL8614635 0.72 TRPA1 (0.55) POLBALDH1A1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113717735-B Positive dielectric anisotropic liquid crystal compound, liquid crystal composition and liquid crystal display device 烟台显华科技集团股份有限公司 2023-08-08 CN disclosed