Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6850659 | 0.86 | POLB (0.32) | POLBL3MBTL1LPAR1NLRP3 | |
| Hydrochloric Acid SCHEMBL6863878 | 0.81 | POLB (0.35) | POLBLPAR1 | |
| Hydrochloric Acid SCHEMBL5854332 | 0.79 | KCNK3 (0.36) | — | |
| Hydrochloric Acid SCHEMBL5855320 | 0.77 | ITGB1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL6698975 | 0.74 | L3MBTL1 (0.33) | POLBL3MBTL1LPAR1 | |
| Hydrochloric Acid SCHEMBL7108556 | 0.70 | L3MBTL1 (0.34) | POLBL3MBTL1 | |
| Hydrochloric Acid SCHEMBL6700262 | 0.69 | L3MBTL1 (0.33) | POLBL3MBTL1LPAR1 | |
| Hydrochloric Acid SCHEMBL6864729 | 0.69 | L3MBTL1 (0.33) | POLBL3MBTL1LPAR1 | |
| Hydrochloric Acid SCHEMBL5854022 | 0.69 | KCNK3 (0.34) | MAPT | |
| Hydrochloric Acid SCHEMBL5852677 | 0.69 | LMNA (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004106394-A1 | COPOLYMERS OF ETHYLENE AND/OR α-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-12-09 | — | — | WO | disclosed |