SCHEMBL6864920

SCHEMBL6864920

[CH2]CN(CC)S(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA2 P00918 11/20 0.38
MMP1 P03956 11/20 0.36
MMP2 P08253 11/20 0.36
MMP9 P14780 11/20 0.36
MMP8 P22894 11/20 0.36
MMP13 P45452 11/20 0.36
CA1 P00915 8/20 0.36
F2 P00734 4/20 0.33
PRSS1 P07477 4/20 0.33
PRSS2 P07478 4/20 0.33
PRSS3 P35030 4/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1524219 1.00 CA2 (0.38) CA2MMP1MMP2MMP9MMP8
SCHEMBL7630351 1.00 CA2 (0.38) CA2MMP1MMP2MMP9MMP8
SCHEMBL29910639 0.89 CA2 (0.43) CA2MMP1MMP2MMP9MMP8
SCHEMBL9340018 0.87 CA2 (0.40) CA2MMP1MMP2MMP9MMP8
SCHEMBL10355039 0.86 CA2 (0.36) CA2MMP1MMP2MMP9MMP8
SCHEMBL6764713 0.86 CA2 (0.37) CA2MMP1MMP2MMP9MMP8
SCHEMBL11157531 0.86 CA2 (0.36) CA2MMP1MMP2MMP9MMP8
SCHEMBL1524772 0.83 MMP1 (0.39) CA2MMP1MMP2MMP9MMP8
SCHEMBL9561852 0.81 CA2 (0.35) CA2MMP1MMP2MMP9MMP8
SCHEMBL8859579 0.79 CA2 (0.38) CA2MMP1MMP2MMP9MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6797444-B2 A PROTECTIVE LAYER CONTAINING A COUPLING FLUOROPOLYMER PARTICLES DISPERSED IN A COPOLYMER HAVING A FLUORINE ATOM-CONTAINING SILOXANE ADDITION-CONDENSATION PRODUCT IN A SIDE CHAIN; NONABRASIVE, HARDENING KONICA CORPORATION (JP) 2004-09-28 US disclosed
US-20030134209-A1 Electrophotographic photoreceptor and production method of the same KONICA CORPORATION (JP) 2003-07-17 US disclosed
EP-0248421-B1 Carrier for developer FUJI XEROX CO LTD (JP) 1994-09-07 EP disclosed
US-5110703-A Particles of magnetic powder in binder resin blend of polyolefin and olefin polymer having functional group FUJI XEROX CO., LTD. (JP) 1992-05-05 US disclosed
US-4965160-A CHARGE QUALITY FUJI XEROX CO., LTD. (JP) 1990-10-23 US disclosed
US-4954409-A FLUORINATED ACRYLIC POLYMER FUJI XEROX CO., LTD. (JP) 1990-09-04 US disclosed
US-4868083-A Developer carrier and process for producing the same FUJI XEROX CO., LTD. (JP) 1989-09-19 US disclosed
US-4791041-A FLUORINATED ALKYL (METH)ARYLATE COPOLYMER OVERCOATINGS; ANTISOILANTS; ANTISTICKING AGENTS FUJI XEROX CO., LTD. (JP) 1988-12-13 US disclosed
EP-0248421-A2 Carrier for developer FUJI XEROX CO., LTD. (JP) 1987-12-09 EP disclosed