Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 6/20 | 0.48 |
| ▸ | TEC | P42680 | 4/20 | 0.41 |
| ▸ | TXK | P42681 | 4/20 | 0.41 |
| ▸ | BMX | P51813 | 4/20 | 0.41 |
| ▸ | BTK | Q06187 | 4/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ICMT | O60725 | 2/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13505881 | 0.92 | GPR52 (0.49) | GPR52TSHRMAPK1SMN1; SMN2PTGER4 | |
| SCHEMBL6865532 | 0.90 | GPR52 (0.40) | GPR52TECTXKBMXBTK | |
| SCHEMBL6864177 | 0.89 | GPR52 (0.51) | GPR52ATMTSHRMAPK1SMN1; SMN2 | |
| SCHEMBL13506435 | 0.88 | PDE4B (0.48) | GPR52TSHRMAPK1SMN1; SMN2MAPT | |
| SCHEMBL6863891 | 0.86 | GPR52 (0.64) | GPR52PTGER4 | |
| SCHEMBL13506119 | 0.82 | GPR52 (0.40) | GPR52PTGER4 | |
| SCHEMBL6864531 | 0.81 | PDE4B (0.37) | GPR52SMN1; SMN2 | |
| SCHEMBL13506389 | 0.79 | PDE4B (0.46) | GPR52SMN1; SMN2 | |
| SCHEMBL6865068 | 0.79 | GPR52 (0.57) | GPR52 | |
| SCHEMBL6864272 | 0.78 | GPR52 (0.50) | GPR52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2518054-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011078360-A1 | AMIDE COMPOUND | 武田薬品工業株式会社 (JP) | 2011-06-30 | — | — | WO | disclosed |