Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LIPC | P11150 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2237686 | 0.84 | ALDH1A1 (0.49) | TDP1ALDH1A1L3MBTL1TSHRCYP3A4 | |
| SCHEMBL24699730 | 0.81 | ALDH1A1 (0.55) | TDP1ALDH1A1L3MBTL1TSHRCYP3A4 | |
| SCHEMBL16925518 | 0.81 | TSHR (0.49) | LIPGALDH1A1TSHRNPSR1MAPT | |
| SCHEMBL19669288 | 0.78 | TDP1 (0.71) | TDP1ALDH1A1EGLN1L3MBTL1TSHR | |
| SCHEMBL26800815 | 0.78 | TDP1 (0.46) | TDP1ALDH1A1L3MBTL1TSHRCYP3A4 | |
| SCHEMBL26783084 | 0.77 | ALDH1A1 (0.45) | TDP1ALDH1A1L3MBTL1TSHRCYP3A4 | |
| SCHEMBL17848969 | 0.76 | KDM4E (0.47) | ALDH1A1L3MBTL1TSHRKMT2AMAPT | |
| SCHEMBL26783089 | 0.75 | ALDH1A1 (0.43) | TDP1ALDH1A1L3MBTL1TSHRCYP3A4 | |
| SCHEMBL26798889 | 0.75 | ALDH1A1 (0.43) | TDP1ALDH1A1L3MBTL1TSHRCYP3A4 | |
| SCHEMBL26783087 | 0.75 | ALDH1A1 (0.43) | TDP1ALDH1A1L3MBTL1TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0840727-B1 | 3-HYDROXY-2(1H)-PYRIDINONE CHELATING AGENTS | UNIV CALIFORNIA (US) | 2004-05-06 | — | — | EP | disclosed |
| US-5892029-A | HIGHLY EFFECTIVE UPON BOTH INJECTION AND ORAL ADMINISTRATION. | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-04-06 | — | — | US | disclosed |
| EP-0840727-A1 | 3-HYDROXY-2(1H)-PYRIDINONE CHELATING AGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-05-13 | — | — | EP | disclosed |
| US-5624901-A | CARBAMOYL SUBSTITUTED COMPOUNDS FOR CHELATE COMPOUNDS FOR MAGNETIC RESONANCE IMAGING | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-04-29 | — | — | US | disclosed |
| WO-1997000245-A1 | 3-HYDROXY-2(1H)-PYRIDINONE CHELATING AGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-01-03 | — | — | WO | disclosed |