Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6867948 | 0.98 | NPC1 (0.33) | NPC1LMNAPKMHTTRAB9A | |
| Hydrochloric Acid SCHEMBL6869270 | 0.94 | NPC1 (0.35) | NPC1LMNAPKMHTTRAB9A | |
| Hydrochloric Acid SCHEMBL7005381 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL6861519 | 0.86 | PTGS2 (0.35) | — | |
| Hydrochloric Acid SCHEMBL6861431 | 0.82 | MAPK1 (0.34) | LMNAHTT | |
| SCHEMBL7005344 | 0.82 | MAPK1 (0.39) | NPC1LMNAHTTRAB9A | |
| SCHEMBL7007419 | 0.81 | GRM2 (0.33) | PKM | |
| Hydrochloric Acid SCHEMBL6866392 | 0.81 | MAPK1 (0.36) | LMNAHTT | |
| Hydrochloric Acid SCHEMBL7010030 | 0.81 | MAPK1 (0.38) | NPC1LMNAHTTRAB9A | |
| Hydrochloric Acid SCHEMBL8307701 | 0.80 | ALDH1A1 (0.44) | LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091957-B1 | PYRIMIDIN-AMINOMETHYL-PYRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN THE CONTROL OF HELICOBACTER BACTERIA | ALTANA PHARMA AG (DE) | 2004-12-15 | — | — | EP | disclosed |
| US-6395732-B1 | BACTERICIDES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2002-05-28 | — | — | US | disclosed |
| EP-1091957-A1 | PYRIMIDIN-AMINOMETHYL-PYRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN THE CONTROL OF HELICOBACTER BACTERIA | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 2001-04-18 | — | — | EP | disclosed |
| WO-1999061439-A1 | PYRIMIDIN-AMINOMETHYL-PYRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN THE CONTROL OF HELICOBACTER BACTERIA | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1999-12-02 | — | — | WO | disclosed |