Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 7/20 | 0.38 |
| ▸ | NPC1 | O15118 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7010030 | 0.99 | MAPK1 (0.38) | MAPK1HSD17B10RAB9ANPC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7005188 | 0.84 | MAPT (0.36) | HSD17B10RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL7007419 | 0.82 | GRM2 (0.33) | TSHRPARP14 | |
| SCHEMBL6865524 | 0.82 | NPC1 (0.34) | RAB9ANPC1HTTLMNA | |
| Hydrochloric Acid SCHEMBL6867948 | 0.81 | NPC1 (0.33) | RAB9ANPC1HTTLMNA | |
| SCHEMBL8805150 | 0.78 | RAB9A (0.54) | HSD17B10RAB9ANPC1SMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL7099731 | 0.78 | ALDH1A1 (0.44) | HSD17B10SMN1; SMN2KMT2AALDH1A1ALOX15 | |
| Hydrochloric Acid SCHEMBL8430958 | 0.77 | RAB9A (0.53) | HSD17B10RAB9ANPC1SMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL6869270 | 0.77 | NPC1 (0.35) | RAB9ANPC1HTTLMNA | |
| SCHEMBL7807341 | 0.76 | NPC1 (0.58) | MAPK1HSD17B10RAB9ANPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0772593-B1 | THIOPYRIDYL COMPOUNDS FOR CONTROLLING HELICOBACTER BACTERIA | ALTANA PHARMA AG (DE) | 2003-05-02 | — | — | EP | disclosed |
| US-6162809-A | Pyridylthio compounds for controlling helicobacter bacteria | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2000-12-19 | — | — | US | disclosed |
| EP-0772593-A1 | THIOPYRIDYL COMPOUNDS FOR CONTROLLING HELICOBACTER BACTERIA | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1997-05-14 | — | — | EP | disclosed |
| WO-1996002505-A1 | THIOPYRIDYL COMPOUNDS FOR CONTROLLING HELICOBACTER BACTERIA | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1996-02-01 | — | — | WO | disclosed |