Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 2/20 | 0.43 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.43 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.43 |
| ▸ | NAAA | Q02083 | 3/20 | 0.40 |
| ▸ | ICMT | O60725 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | ADH1C | P00326 | 1/20 | 0.39 |
| ▸ | ADH1A | P07327 | 1/20 | 0.39 |
| ▸ | ADH4 | P08319 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexylamine SCHEMBL6863578 | 1.00 | GNAI3 (0.43) | GNAI3GNAO1GNAI1NAAAICMT | |
| Octane SCHEMBL27874847 | 0.87 | GNAI3 (0.52) | GNAI3GNAO1GNAI1NAAACYP1A2 | |
| Cyclohexylamine SCHEMBL588721 | 0.85 | CYP1A2 (0.50) | GNAI3GNAO1GNAI1NAAACYP1A2 | |
| Cyclohexylamine SCHEMBL6864569 | 0.83 | ADH1A (0.41) | GNAI3GNAO1GNAI1ADH1CADH1A | |
| Cyclohexane SCHEMBL16209664 | 0.82 | DNM1 (0.52) | ICMTALBADH1CADH1AADH4 | |
| Cyclohexylamine SCHEMBL29057250 | 0.80 | CYP1A2 (0.50) | GNAI3GNAO1GNAI1NAAACYP1A2 | |
| Cyclohexylamine SCHEMBL6865056 | 0.79 | DNM1 (0.56) | GNAI3GNAO1GNAI1NAAACYP1A2 | |
| Dodecylamine SCHEMBL11756736 | 0.79 | DNM1 (0.56) | GNAI3GNAO1GNAI1NAAACYP1A2 | |
| Cyclohexylamine SCHEMBL3138481 | 0.79 | DNM1 (0.56) | GNAI3GNAO1GNAI1NAAACYP1A2 | |
| Cyclohexylamine SCHEMBL6865558 | 0.79 | DNM1 (0.56) | GNAI3GNAO1GNAI1NAAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6806289-B1 | SUCH AS AMMINE (2-AMINO-3-PICOLINE) DICHLOROPLATINUM(II); EFFICIENCY AND SELECTIVITY FOR DESTROYING TRANSFORMED CELLS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-10-19 | — | — | US | disclosed |