Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.35 |
| ▸ | FECH | P22830 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1552819 | 0.75 | DRD2 (0.40) | SLC6A2SLC6A4EPHA2 | |
| SCHEMBL1552555 | 0.73 | DRD2 (0.40) | SLC6A2SLC6A4EPHA2 | |
| SCHEMBL1552559 | 0.73 | DRD2 (0.40) | SLC6A2SLC6A4EPHA2 | |
| SCHEMBL17351215 | 0.72 | MAPT (0.36) | MAPK1 | |
| SCHEMBL6555185 | 0.70 | CNR2 (0.47) | MAPK1 | |
| SCHEMBL4026296 | 0.70 | CHEK1 (0.39) | SLC6A2SLC6A4CHEK1KCNH2 | |
| Hydrochloric Acid SCHEMBL10413246 | 0.69 | CHEK1 (0.39) | SLC6A2SLC6A4CHEK1KCNH2 | |
| SCHEMBL6555370 | 0.68 | LMNA (0.44) | — | |
| SCHEMBL27496539 | 0.68 | SLC6A4 (0.41) | SLC6A2SLC6A4MAPK1 | |
| SCHEMBL1551940 | 0.68 | SLC6A4 (0.42) | SLC6A2SLC6A4EPHA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6821980-B1 | Substituted 5-benzyl-2,4-diaminopyrimidines | BASILEA PHARMACEUTICA AG (CH) | 2004-11-23 | — | — | US | disclosed |