Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6866526 | 0.68 | KDM4E (0.58) | L3MBTL1TDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL1728403 | 0.59 | RAB9A (0.59) | L3MBTL1ALDH1A1KMT2AMEN1GAA | |
| SCHEMBL28708338 | 0.58 | KCNA3 (0.58) | L3MBTL1TDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL8671561 | 0.57 | KCNA3 (0.64) | L3MBTL1ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL14499849 | 0.57 | KCNA3 (0.64) | L3MBTL1TDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL10873329 | 0.56 | PKM (0.50) | L3MBTL1TDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL3902195 | 0.56 | ALDH1A1 (0.84) | L3MBTL1TDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL11300555 | 0.56 | KCNA3 (0.61) | L3MBTL1ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL57755 | 0.55 | KCNA3 (0.67) | ALDH1A1RAB9AMAPT | |
| SCHEMBL7295306 | 0.55 | NPC1 (0.57) | L3MBTL1TDP1ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6806273-B1 | 5-THIO-THIAZOLO(4,5-D)PYRIMIDIN-7-YL DERIVATIVES; CHEMOKINE RECEPTOR (ESPECIALLY CXCR2) ACTIVITY MODULATORS | ASTRAZENECA AB (SE) | 2004-10-19 | — | — | US | disclosed |