Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 20/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | CA4 | P22748 | 1/20 | 0.56 |
| ▸ | CA6 | P23280 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8213068 | 1.00 | STS (0.56) | STSCA1CA2CA9ESR1 | |
| SCHEMBL8217658 | 0.89 | STS (0.46) | STSCA1CA2CA9ESR1 | |
| SCHEMBL8217657 | 0.89 | STS (0.46) | STSCA1CA2CA9ESR1 | |
| SCHEMBL9628599 | 0.87 | LMNA (0.52) | STSESR1ESR2 | |
| SCHEMBL6364943 | 0.86 | STS (0.44) | STSCA1CA2CA9ESR1 | |
| SCHEMBL6364938 | 0.86 | STS (0.44) | STSCA1CA2CA9ESR1 | |
| SCHEMBL9725114 | 0.82 | ESR1 (0.50) | STSESR1ESR2 | |
| SCHEMBL9148557 | 0.82 | ESR1 (0.50) | STSESR1ESR2 | |
| SCHEMBL6861299 | 0.78 | STS (0.59) | STSCA1CA2CA9ESR1 | |
| SCHEMBL8214206 | 0.78 | STS (0.59) | STSCA1CA2CA9ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775155-B1 | ESTRA-1,3,5(10)-TRIENE DERIVATIVES, METHODS OF PREPARING SUCH COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING AG (DE) | 2004-05-06 | — | — | EP | claimed |
| US-6080735-A | SUITABLE FOR HORMONAL CONTRACEPTION AND CLIMACTERIC HORMONE REPLACEMENT THERAPY (HRT) AS WELL AS FOR TREATMENT OF GYNECOLOGICAL AND ANDROLOGICAL DISEASES | JENAPHARM GMBH & CO. KG (DE) | 2000-06-27 | — | — | US | claimed |
| US-6080735-A | SUITABLE FOR HORMONAL CONTRACEPTION AND CLIMACTERIC HORMONE REPLACEMENT THERAPY (HRT) AS WELL AS FOR TREATMENT OF GYNECOLOGICAL AND ANDROLOGICAL DISEASES | JENAPHARM GMBH & CO. KG (DE) | 2000-06-27 | — | — | US | disclosed |