Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 5/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | STS | P08842 | 6/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8217658 | 0.87 | STS (0.46) | LMNAHSD17B1MAPTRECQLSMN1; SMN2 | |
| SCHEMBL8217657 | 0.87 | STS (0.46) | LMNAHSD17B1MAPTRECQLSMN1; SMN2 | |
| SCHEMBL8213068 | 0.87 | STS (0.56) | ESR1STSESR2 | |
| SCHEMBL6867283 | 0.87 | STS (0.56) | ESR1STSESR2 | |
| SCHEMBL9148557 | 0.86 | ESR1 (0.50) | LMNAHSD17B1MAPTRECQLSMN1; SMN2 | |
| SCHEMBL9725114 | 0.86 | ESR1 (0.50) | LMNAHSD17B1MAPTRECQLSMN1; SMN2 | |
| SCHEMBL15979563 | 0.85 | LMNA (0.52) | LMNAHSD17B1MAPTRECQLSMN1; SMN2 | |
| SCHEMBL6364938 | 0.85 | STS (0.44) | LMNAHSD17B1MAPTRECQLSMN1; SMN2 | |
| SCHEMBL6364943 | 0.85 | STS (0.44) | LMNAHSD17B1MAPTRECQLSMN1; SMN2 | |
| SCHEMBL8055169 | 0.83 | LMNA (0.51) | LMNAHSD17B1MAPTRECQLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4789671-A | ESTROGENIC ACTIVITY | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-12-06 | — | — | US | claimed |
| EP-0318490-B1 | 14,17-G(B)-ETHANO-14-G(B)-ESTRATRIENES, PROCESS FOR THEIR MANUFACTURE AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-01-29 | — | — | EP | disclosed |
| US-4789671-A | ESTROGENIC ACTIVITY | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-12-06 | — | — | US | disclosed |