Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 11/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 3/20 | 0.46 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8217658 | 1.00 | STS (0.46) | STSABCC4ABCC1CYP2C9SLCO1B1 | |
| SCHEMBL6364943 | 0.90 | STS (0.44) | STSABCC4ABCC1CYP2C9SLCO1B1 | |
| SCHEMBL6364938 | 0.90 | STS (0.44) | STSABCC4ABCC1CYP2C9SLCO1B1 | |
| SCHEMBL6867283 | 0.89 | STS (0.56) | STSCA1CA2CA9ESR1 | |
| SCHEMBL8213068 | 0.89 | STS (0.56) | STSCA1CA2CA9ESR1 | |
| SCHEMBL9628599 | 0.87 | LMNA (0.52) | STSABCC4ABCC1CYP2C9SLCO1B1 | |
| SCHEMBL9725114 | 0.81 | ESR1 (0.50) | STSCYP2C9ESR1ESR2CYP3A4 | |
| SCHEMBL9148557 | 0.81 | ESR1 (0.50) | STSCYP2C9ESR1ESR2CYP3A4 | |
| SCHEMBL8055169 | 0.74 | LMNA (0.51) | STSABCC4ABCC1CYP2C9SLCO1B1 | |
| SCHEMBL8056152 | 0.74 | LMNA (0.51) | STSABCC4ABCC1CYP2C9SLCO1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080735-A | SUITABLE FOR HORMONAL CONTRACEPTION AND CLIMACTERIC HORMONE REPLACEMENT THERAPY (HRT) AS WELL AS FOR TREATMENT OF GYNECOLOGICAL AND ANDROLOGICAL DISEASES | JENAPHARM GMBH & CO. KG (DE) | 2000-06-27 | — | — | US | claimed |