Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | SHBG | P04278 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexylamine SCHEMBL6868400 | 0.80 | MMP8 (0.43) | MMP8MMP1MMP2SHBGSMYD3 | |
| Cyclohexylamine SCHEMBL27864694 | 0.78 | TP53 (0.42) | MMP8MMP1MMP2SHBGEPHX1 | |
| Cyclohexylamine SCHEMBL7039293 | 0.78 | MMP8 (0.38) | MMP8MMP1MMP2SHBGEPHX1 | |
| Cyclohexylamine SCHEMBL4447887 | 0.77 | SHBG (0.39) | MMP8MMP1MMP2SHBGALDH1A1 | |
| Cyclohexylamine SCHEMBL8950184 | 0.75 | TDP1 (0.44) | MMP8MMP1MMP2 | |
| Cyclohexylamine SCHEMBL2067439 | 0.75 | CYP1A2 (0.42) | MMP8MMP1MMP2SHBGALDH1A1 | |
| Cyclohexylamine SCHEMBL20703173 | 0.75 | EPHX1 (0.38) | MMP8MMP1MMP2SHBGEPHX1 | |
| Cyclohexylamine SCHEMBL10905650 | 0.75 | MMP8 (0.41) | MMP8MMP1MMP2 | |
| Methylamine SCHEMBL6865611 | 0.74 | — | — | |
| SCHEMBL3608 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6806289-B1 | SUCH AS AMMINE (2-AMINO-3-PICOLINE) DICHLOROPLATINUM(II); EFFICIENCY AND SELECTIVITY FOR DESTROYING TRANSFORMED CELLS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-10-19 | — | — | US | disclosed |