Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexylamine SCHEMBL27864694 | 0.84 | TP53 (0.42) | MMP8MMP1MMP2ALDH1A1SHBG | |
| Cyclohexylamine SCHEMBL28122067 | 0.83 | TP53 (0.36) | MMP8MMP1MMP2ALDH1A1SHBG | |
| Cyclohexylamine SCHEMBL6868335 | 0.83 | SIGMAR1 (0.41) | MMP8MMP1MMP2SIGMAR1ALDH1A1 | |
| Cyclohexylamine SCHEMBL4447887 | 0.83 | SHBG (0.39) | MMP8MMP1MMP2ALDH1A1SHBG | |
| Cyclohexylamine SCHEMBL4239622 | 0.83 | THRB (0.39) | MMP8MMP1MMP2ALDH1A1THRB | |
| Cyclohexylamine SCHEMBL28121443 | 0.81 | TP53 (0.35) | MMP8MMP1MMP2ALDH1A1 | |
| Cyclohexylamine SCHEMBL6868400 | 0.81 | MMP8 (0.43) | MMP8MMP1MMP2SHBGTHRB | |
| Cyclohexylamine SCHEMBL20703173 | 0.80 | EPHX1 (0.38) | MMP8MMP1MMP2ALDH1A1SHBG | |
| Cyclohexylamine SCHEMBL2067439 | 0.80 | CYP1A2 (0.42) | MMP8MMP1MMP2ALDH1A1SHBG | |
| Cyclohexylamine SCHEMBL6867493 | 0.80 | SIGMAR1 (0.47) | MMP8MMP2SIGMAR1EPHX1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6806289-B1 | SUCH AS AMMINE (2-AMINO-3-PICOLINE) DICHLOROPLATINUM(II); EFFICIENCY AND SELECTIVITY FOR DESTROYING TRANSFORMED CELLS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-10-19 | — | — | US | disclosed |