Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.42 |
| ▸ | TACR3 | P29371 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6867524 | 1.00 | ELANE (0.44) | ELANEMCHR1P2RY12TACR3L3MBTL1 | |
| SCHEMBL6456529 | 0.93 | TACR3 (0.47) | MCHR1TACR3L3MBTL1ADRA2AATM | |
| SCHEMBL6456527 | 0.93 | TACR3 (0.47) | MCHR1TACR3L3MBTL1ADRA2AATM | |
| SCHEMBL27651737 | 0.91 | MCHR1 (0.45) | MCHR1ADRA2AKDM4ELMNASMN1; SMN2 | |
| SCHEMBL6876320 | 0.90 | MCHR1 (0.41) | MCHR1ADRA2A | |
| SCHEMBL4210512 | 0.84 | MCHR1 (0.55) | ELANEMCHR1ADRA2A | |
| SCHEMBL4035978 | 0.84 | MCHR1 (0.55) | ELANEMCHR1ADRA2A | |
| SCHEMBL27632422 | 0.82 | ALDH1A1 (0.43) | MCHR1ADRA2AKDM4ELMNASMN1; SMN2 | |
| SCHEMBL6879678 | 0.81 | TSHR (0.54) | MCHR1ADRA2ALMNATSHR | |
| SCHEMBL6879682 | 0.81 | TSHR (0.54) | MCHR1ADRA2ALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |