Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 2/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.35 |
| ▸ | JAK3 | P52333 | 3/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | PAK4 | O96013 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PRKACA | P17612 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6867614 | 1.00 | MAPK8 (0.39) | MAPK8MAPK9MAPK10MAPK14DRD2 | |
| SCHEMBL6877019 | 0.86 | MAPK8 (0.39) | MAPK8MAPK9MAPK10MAPK14DRD2 | |
| SCHEMBL6877016 | 0.86 | MAPK8 (0.39) | MAPK8MAPK9MAPK10MAPK14DRD2 | |
| SCHEMBL6873422 | 0.82 | MAPK14 (0.40) | MAPK8MAPK9MAPK10MAPK14DRD2 | |
| SCHEMBL6873416 | 0.82 | MAPK14 (0.40) | MAPK8MAPK9MAPK10MAPK14DRD2 | |
| SCHEMBL6879294 | 0.81 | MAPK14 (0.40) | MAPK8MAPK9MAPK10MAPK14DRD2 | |
| SCHEMBL6879291 | 0.81 | MAPK14 (0.40) | MAPK8MAPK9MAPK10MAPK14DRD2 | |
| SCHEMBL6872401 | 0.81 | ACHE (0.42) | MAPK8MAPK9MAPK10MAPK14DRD2 | |
| SCHEMBL6872392 | 0.81 | ACHE (0.42) | MAPK8MAPK9MAPK10MAPK14DRD2 | |
| SCHEMBL6867360 | 0.80 | MAPK14 (0.39) | MAPK14DRD2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |