Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6857593 | 0.90 | SMN1; SMN2 (0.64) | SMN1; SMN2LMNAPOLBALDH1A1HTT | |
| SCHEMBL14535420 | 0.84 | ALDH1A1 (0.59) | SMN1; SMN2LMNAPOLBALDH1A1HTT | |
| SCHEMBL14701528 | 0.84 | ALDH1A1 (0.59) | SMN1; SMN2LMNAPOLBALDH1A1HTT | |
| SCHEMBL8915928 | 0.84 | SMN1; SMN2 (0.43) | SMN1; SMN2LMNAPOLBALDH1A1KMT2A | |
| SCHEMBL13188052 | 0.84 | SMN1; SMN2 (0.43) | SMN1; SMN2LMNAPOLBALDH1A1KMT2A | |
| SCHEMBL8917409 | 0.84 | SMN1; SMN2 (0.43) | SMN1; SMN2LMNAPOLBALDH1A1KMT2A | |
| SCHEMBL24932572 | 0.83 | ALDH1A1 (0.54) | LMNAPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL14224491 | 0.83 | RIPK1 (0.62) | SMN1; SMN2LMNAPOLBALDH1A1HTT | |
| SCHEMBL14224547 | 0.83 | RIPK1 (0.62) | SMN1; SMN2LMNAPOLBALDH1A1HTT | |
| SCHEMBL8558646 | 0.83 | RIPK1 (0.55) | SMN1; SMN2LMNAPOLBALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110268694-A1 | METHODS FOR TREATING VASCULAR LEAK SYNDROME | EyePoint Pharmaceuticals, Inc. | 2011-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110268694-A1 | METHODS FOR TREATING VASCULAR LEAK SYNDROME | ICAM1, VCAM1, VIPR2 | SMN1; SMN2 2103/4885LMNA 900/4885POLB 3185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.