Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA3 | P07451 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA6 | P23280 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 10/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16416350 | 0.98 | CPB2 (0.41) | CA12CA1CA2CA3CA4 | |
| SCHEMBL11967584 | 0.98 | CPB2 (0.41) | CA12CA1CA2CA3CA4 | |
| SCHEMBL27975115 | 0.97 | GRIN2D (0.38) | CA12CA1CA2CA3CA4 | |
| SCHEMBL7862753 | 0.95 | DNM1 (0.40) | CA12CA1CA2CA3CA4 | |
| Bromide SCHEMBL5164587 | 0.93 | DNM1 (0.38) | CA12CA1CA2CA3CA4 | |
| SCHEMBL9551519 | 0.90 | GRIN2D (0.36) | CA12CA1CA2CA3CA4 | |
| SCHEMBL3193842 | 0.87 | GRIN2D (0.34) | CPB2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL24838601 | 0.87 | — | — | |
| SCHEMBL30895346 | 0.78 | GRIN2D (0.39) | CA12CA1CA2CA3CA4 | |
| SCHEMBL744988 | 0.78 | TSHR (0.31) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0859018-B1 | Process for the preparation of a homogeneous polyol component stable to demixing | BASF AG (DE) | 2004-11-24 | — | — | EP | disclosed |
| EP-0859018-A1 | Process for the preparation of a homogeneous polyol component stable to demixing | BASF AKTIENGESELLSCHAFT (DE) | 1998-08-19 | — | — | EP | disclosed |
| US-4381405-A | Process for the preparation of polymethylene polyphenyl polyisocyanate composition | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1983-04-26 | — | — | US | disclosed |