Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 7/20 | 0.36 |
| ▸ | BCHE | P06276 | 3/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6868077 | 1.00 | MCHR1 (0.43) | MCHR1ADRA2AKMT2AMEN1MAPT | |
| SCHEMBL6868067 | 1.00 | MCHR1 (0.43) | MCHR1ADRA2AKMT2AMEN1MAPT | |
| SCHEMBL6875905 | 0.86 | MCHR1 (0.42) | MCHR1ADRA2AKMT2AMEN1MAPT | |
| SCHEMBL6875886 | 0.86 | MCHR1 (0.42) | MCHR1ADRA2AKMT2AMEN1MAPT | |
| SCHEMBL6875896 | 0.86 | MCHR1 (0.42) | MCHR1ADRA2AKMT2AMEN1MAPT | |
| SCHEMBL6868116 | 0.82 | MCHR1 (0.56) | MCHR1ADRA2AKMT2AMAPTHTT | |
| SCHEMBL6868112 | 0.82 | MCHR1 (0.56) | MCHR1ADRA2AKMT2AMAPTHTT | |
| SCHEMBL6874339 | 0.82 | ADRA2A (0.44) | MCHR1ADRA2AKMT2AMEN1MAPT | |
| SCHEMBL27652714 | 0.81 | MCHR1 (0.43) | MCHR1ADRA2AHTTALDH1A1HRH1 | |
| SCHEMBL27652712 | 0.81 | MCHR1 (0.43) | MCHR1ADRA2AHTTALDH1A1HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |