Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6868226 | 1.00 | BCHE (0.46) | BCHEACHESMN1; SMN2ALOX12LMNA | |
| SCHEMBL6872800 | 0.91 | MCHR1 (0.46) | BCHEACHESMN1; SMN2KMT2AADRA2A | |
| SCHEMBL6872807 | 0.91 | MCHR1 (0.46) | BCHEACHESMN1; SMN2KMT2AADRA2A | |
| SCHEMBL6876262 | 0.90 | SMN1; SMN2 (0.55) | BCHEACHESMN1; SMN2ALOX12LMNA | |
| SCHEMBL6872663 | 0.90 | MEN1 (0.52) | SMN1; SMN2ALOX12LMNAKMT2AMAPT | |
| SCHEMBL6872661 | 0.90 | MEN1 (0.52) | SMN1; SMN2ALOX12LMNAKMT2AMAPT | |
| SCHEMBL6878840 | 0.89 | SMN1; SMN2 (0.52) | SMN1; SMN2ALOX12LMNAKMT2AADRA2A | |
| SCHEMBL6878845 | 0.89 | SMN1; SMN2 (0.52) | SMN1; SMN2ALOX12LMNAKMT2AADRA2A | |
| SCHEMBL6878795 | 0.89 | SMN1; SMN2 (0.43) | SMN1; SMN2ALOX12LMNAKMT2AADRA2A | |
| SCHEMBL6878792 | 0.89 | SMN1; SMN2 (0.43) | SMN1; SMN2ALOX12LMNAKMT2AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |